The nuclear trafficking of extracellular fibroblast growth factor (FGF)-1 correlates with the perinuclear association of the FGF receptor-1alpha isoforms but not the FGF receptor-1beta isoforms.
Prudovsky IA, Savion N, LaVallee TM, Maciag T.
Prudovsky IA, et al. Among authors: savion n.
J Biol Chem. 1996 Jun 14;271(24):14198-205. doi: 10.1074/jbc.271.24.14198.
J Biol Chem. 1996.
PMID: 8662999
Free article.
We have previously shown that in cells irreversibly committed to DNA synthesis by FGF-1, approximately 15% of cell surface FGFR-1 traffics to a perinuclear locale as a structurally intact and functional tyrosine kinase (Prudovsky, I., Savion, N., Zhan, X., Friesel, …
We have previously shown that in cells irreversibly committed to DNA synthesis by FGF-1, approximately 15% of cell surface FGFR-1 traffics t …