Saydoff JA - Search Results

1

Cellular delivery of human CNTF prevents motor and cognitive dysfunction in a rodent model of Huntington's disease.

Emerich DF, Cain CK, Greco C, Saydoff JA, Hu ZY, Liu H, Lindner MD. Emerich DF, et al. Among authors: saydoff ja. Cell Transplant. 1997 May-Jun;6(3):249-66. doi: 10.1177/096368979700600308. Cell Transplant. 1997. PMID: 9171158

2

Intrathecal polymer-encapsulated bovine adrenal chromaffin cells fail to produce analgesic effects in the hotplate and formalin test.

Lindner MD, Francis JM, Saydoff JA. Lindner MD, et al. Among authors: saydoff ja. Exp Neurol. 2000 Oct;165(2):370-83. doi: 10.1006/exnr.2000.7472. Exp Neurol. 2000. PMID: 10993696

3

The analgesic potential of intraventricular polymer-encapsulated adrenal chromaffin cells in a rodent model of chronic neuropathic pain.

Lindner MD, Francis JM, Plone MA, McDermott PE, Frydel BR, Emerich DF, Saydoff JA. Lindner MD, et al. Among authors: saydoff ja. Exp Clin Psychopharmacol. 2000 Nov;8(4):524-38. doi: 10.1037//1064-1297.8.4.524. Exp Clin Psychopharmacol. 2000. PMID: 11127424

4

Numerous adrenal chromaffin cell preparations fail to produce analgesic effects in the formalin test or in tests of acute pain even with nicotine stimulation.

Lindner MD, Francis JM, McDermott PE, Bell WJ, Blaney TJ, Sherman SS, Saydoff JA. Lindner MD, et al. Among authors: saydoff ja. Pain. 2000 Nov;88(2):177-188. doi: 10.1016/S0304-3959(00)00324-9. Pain. 2000. PMID: 11050373

5

Polymer-encapsulated PC-12 cells demonstrate high-affinity uptake of dopamine in vitro and 18F-Dopa uptake and metabolism after intracerebral implantation in nonhuman primates.

Subramanian T, Emerich DF, Bakay RA, Hoffman JM, Goodman MM, Shoup TM, Miller GW, Levey AI, Hubert GW, Batchelor S, Winn SR, Saydoff JA, Watts RL. Subramanian T, et al. Among authors: saydoff ja. Cell Transplant. 1997 Sep-Oct;6(5):469-77. doi: 10.1177/096368979700600506. Cell Transplant. 1997. PMID: 9331498

6

No detectable analgesic effects in the formalin test even with one million bovine adrenal chromaffin cells.

Gulwadi AG, Hoane MR, Saydoff JA, Frydel BR, Lindner MD. Gulwadi AG, et al. Among authors: saydoff ja. Pain. 2002 Sep;99(1-2):263-71. doi: 10.1016/s0304-3959(02)00120-3. Pain. 2002. PMID: 12237204

7

Oral uridine pro-drug PN401 decreases neurodegeneration, behavioral impairment, weight loss and mortality in the 3-nitropropionic acid mitochondrial toxin model of Huntington's disease.

Saydoff JA, Liu LS, Garcia RA, Hu Z, Li D, von Borstel RW. Saydoff JA, et al. Brain Res. 2003 Dec 19;994(1):44-54. doi: 10.1016/j.brainres.2003.09.049. Brain Res. 2003. PMID: 14642447

8

Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease.

Saydoff JA, Garcia RA, Browne SE, Liu L, Sheng J, Brenneman D, Hu Z, Cardin S, Gonzalez A, von Borstel RW, Gregorio J, Burr H, Beal MF. Saydoff JA, et al. Neurobiol Dis. 2006 Dec;24(3):455-65. doi: 10.1016/j.nbd.2006.08.011. Epub 2006 Sep 29. Neurobiol Dis. 2006. PMID: 17011205

9

Uridine prodrug improves memory in Tg2576 and TAPP mice and reduces pathological factors associated with Alzheimer's disease in related models.

Saydoff JA, Olariu A, Sheng J, Hu Z, Li Q, Garcia R, Pei J, Sun GY, von Borstel R. Saydoff JA, et al. J Alzheimers Dis. 2013;36(4):637-57. doi: 10.3233/JAD-130059. J Alzheimers Dis. 2013. PMID: 23648515

10

Severe cytochrome c oxidase inhibition in vivo does not induce a pyrimidine deficiency; neuroprotective action of oral uridine prodrug PN401 requires supraphysiological levels of uridine.

Garcia RA, Liu L, Hu Z, Gonzalez A, von Borstel RW, Saydoff JA. Garcia RA, et al. Among authors: saydoff ja. Brain Res. 2005 Dec 20;1066(1-2):164-71. doi: 10.1016/j.brainres.2005.10.056. Epub 2005 Dec 5. Brain Res. 2005. PMID: 16330000

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