Schaefer M - Search Results

1

Discovery and characterization of a positive allosteric modulator of transient receptor potential canonical 6 (TRPC6) channels.

Häfner S, Urban N, Schaefer M. Häfner S, et al. Among authors: schaefer m. Cell Calcium. 2019 Mar;78:26-34. doi: 10.1016/j.ceca.2018.12.009. Epub 2018 Dec 21. Cell Calcium. 2019. PMID: 30594060

2

FRET-based analysis of TRPC subunit stoichiometry.

Amiri H, Schultz G, Schaefer M. Amiri H, et al. Among authors: schaefer m. Cell Calcium. 2003 May-Jun;33(5-6):463-70. doi: 10.1016/s0143-4160(03)00061-7. Cell Calcium. 2003. PMID: 12765691

3

Clemastine potentiates the human P2X7 receptor by sensitizing it to lower ATP concentrations.

Nörenberg W, Hempel C, Urban N, Sobottka H, Illes P, Schaefer M. Nörenberg W, et al. Among authors: schaefer m. J Biol Chem. 2011 Apr 1;286(13):11067-81. doi: 10.1074/jbc.M110.198879. Epub 2011 Jan 24. J Biol Chem. 2011. PMID: 21262970 Free PMC article.

4

Novel pharmacological TRPC inhibitors block hypoxia-induced vasoconstriction.

Urban N, Hill K, Wang L, Kuebler WM, Schaefer M. Urban N, et al. Among authors: schaefer m. Cell Calcium. 2012 Feb;51(2):194-206. doi: 10.1016/j.ceca.2012.01.001. Epub 2012 Jan 24. Cell Calcium. 2012. PMID: 22280812

5

Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors.

Nörenberg W, Sobottka H, Hempel C, Plötz T, Fischer W, Schmalzing G, Schaefer M. Nörenberg W, et al. Among authors: schaefer m. Br J Pharmacol. 2012 Sep;167(1):48-66. doi: 10.1111/j.1476-5381.2012.01987.x. Br J Pharmacol. 2012. PMID: 22506590 Free PMC article.

6

Apomorphine is a bimodal modulator of TRPA1 channels.

Schulze A, Oehler B, Urban N, Schaefer M, Hill K. Schulze A, et al. Among authors: schaefer m. Mol Pharmacol. 2013 Feb;83(2):542-51. doi: 10.1124/mol.112.081976. Epub 2012 Dec 6. Mol Pharmacol. 2013. PMID: 23220749

7

The phenothiazine-class antipsychotic drugs prochlorperazine and trifluoperazine are potent allosteric modulators of the human P2X7 receptor.

Hempel C, Nörenberg W, Sobottka H, Urban N, Nicke A, Fischer W, Schaefer M. Hempel C, et al. Among authors: schaefer m. Neuropharmacology. 2013 Dec;75:365-79. doi: 10.1016/j.neuropharm.2013.07.027. Epub 2013 Aug 14. Neuropharmacology. 2013. PMID: 23954492

8

Riluzole activates TRPC5 channels independently of PLC activity.

Richter JM, Schaefer M, Hill K. Richter JM, et al. Among authors: schaefer m. Br J Pharmacol. 2014 Jan;171(1):158-70. doi: 10.1111/bph.12436. Br J Pharmacol. 2014. PMID: 24117252 Free PMC article.

9

Natural compounds with P2X7 receptor-modulating properties.

Fischer W, Urban N, Immig K, Franke H, Schaefer M. Fischer W, et al. Among authors: schaefer m. Purinergic Signal. 2014;10(2):313-26. doi: 10.1007/s11302-013-9392-1. Epub 2013 Oct 27. Purinergic Signal. 2014. PMID: 24163006 Free PMC article.

10

Cholesterol sensitises the transient receptor potential channel TRPV3 to lower temperatures and activator concentrations.

Klein AS, Tannert A, Schaefer M. Klein AS, et al. Among authors: schaefer m. Cell Calcium. 2014 Jan;55(1):59-68. doi: 10.1016/j.ceca.2013.12.001. Epub 2013 Dec 17. Cell Calcium. 2014. PMID: 24406294

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