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Self-inactivating retroviral vectors with improved RNA processing.
Kraunus J, Schaumann DH, Meyer J, Modlich U, Fehse B, Brandenburg G, von Laer D, Klump H, Schambach A, Bohne J, Baum C. Kraunus J, et al. Among authors: schambach a. Gene Ther. 2004 Nov;11(21):1568-78. doi: 10.1038/sj.gt.3302309. Gene Ther. 2004. PMID: 15372067
Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery.
Galla M, Schambach A, Falk CS, Maetzig T, Kuehle J, Lange K, Zychlinski D, Heinz N, Brugman MH, Göhring G, Izsvák Z, Ivics Z, Baum C. Galla M, et al. Among authors: schambach a. Nucleic Acids Res. 2011 Sep 1;39(16):7147-60. doi: 10.1093/nar/gkr384. Epub 2011 May 23. Nucleic Acids Res. 2011. PMID: 21609958 Free PMC article.
Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells.
Grabundzija I, Wang J, Sebe A, Erdei Z, Kajdi R, Devaraj A, Steinemann D, Szuhai K, Stein U, Cantz T, Schambach A, Baum C, Izsvák Z, Sarkadi B, Ivics Z. Grabundzija I, et al. Among authors: schambach a. Nucleic Acids Res. 2013 Feb 1;41(3):1829-47. doi: 10.1093/nar/gks1305. Epub 2012 Dec 28. Nucleic Acids Res. 2013. PMID: 23275558 Free PMC article.
A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.
Müller-Kuller U, Ackermann M, Kolodziej S, Brendel C, Fritsch J, Lachmann N, Kunkel H, Lausen J, Schambach A, Moritz T, Grez M. Müller-Kuller U, et al. Among authors: schambach a. Nucleic Acids Res. 2015 Feb 18;43(3):1577-92. doi: 10.1093/nar/gkv019. Epub 2015 Jan 20. Nucleic Acids Res. 2015. PMID: 25605798 Free PMC article.
Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice.
Hauber I, Hofmann-Sieber H, Chemnitz J, Dubrau D, Chusainow J, Stucka R, Hartjen P, Schambach A, Ziegler P, Hackmann K, Schröck E, Schumacher U, Lindner C, Grundhoff A, Baum C, Manz MG, Buchholz F, Hauber J. Hauber I, et al. Among authors: schambach a. PLoS Pathog. 2013;9(9):e1003587. doi: 10.1371/journal.ppat.1003587. Epub 2013 Sep 26. PLoS Pathog. 2013. PMID: 24086129 Free PMC article.
Protein transduction from retroviral Gag precursors.
Voelkel C, Galla M, Maetzig T, Warlich E, Kuehle J, Zychlinski D, Bode J, Cantz T, Schambach A, Baum C. Voelkel C, et al. Among authors: schambach a. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7805-10. doi: 10.1073/pnas.0914517107. Epub 2010 Apr 12. Proc Natl Acad Sci U S A. 2010. PMID: 20385817 Free PMC article.
358 results