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Peptoid-Peptide hybrid ligands targeting the polo box domain of polo-like kinase 1.
Chembiochem. 2012 Jun 18;13(9):1291-6. doi: 10.1002/cbic.201200206. Epub 2012 May 8.
Chembiochem. 2012.
PMID: 22570300
Free PMC article.
Identification of high affinity polo-like kinase 1 (Plk1) polo-box domain binding peptides using oxime-based diversification.
Liu F, Park JE, Qian WJ, Lim D, Scharow A, Berg T, Yaffe MB, Lee KS, Burke TR Jr.
Liu F, et al. Among authors: scharow a.
ACS Chem Biol. 2012 May 18;7(5):805-10. doi: 10.1021/cb200469a. Epub 2012 Feb 14.
ACS Chem Biol. 2012.
PMID: 22292814
Free PMC article.
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Development of Bifunctional Inhibitors of Polo-Like Kinase 1 with Low-Nanomolar Activities Against the Polo-Box Domain.
Scharow A, Knappe D, Reindl W, Hoffmann R, Berg T.
Scharow A, et al.
Chembiochem. 2016 Apr 15;17(8):759-67. doi: 10.1002/cbic.201500535. Epub 2015 Dec 4.
Chembiochem. 2016.
PMID: 26634982
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Selective Degradation of Polo-like Kinase 1 by a Hydrophobically Tagged Inhibitor of the Polo-Box Domain.
Rubner S, Scharow A, Schubert S, Berg T.
Rubner S, et al. Among authors: scharow a.
Angew Chem Int Ed Engl. 2018 Dec 21;57(52):17043-17047. doi: 10.1002/anie.201809640. Epub 2018 Nov 27.
Angew Chem Int Ed Engl. 2018.
PMID: 30351497
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Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells.
Scharow A, Raab M, Saxena K, Sreeramulu S, Kudlinzki D, Gande S, Dötsch C, Kurunci-Csacsko E, Klaeger S, Kuster B, Schwalbe H, Strebhardt K, Berg T.
Scharow A, et al.
ACS Chem Biol. 2015 Nov 20;10(11):2570-9. doi: 10.1021/acschembio.5b00565. Epub 2015 Aug 27.
ACS Chem Biol. 2015.
PMID: 26279064
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Nanomolar inhibitors of the transcription factor STAT5b with high selectivity over STAT5a.
Elumalai N, Berg A, Natarajan K, Scharow A, Berg T.
Elumalai N, et al. Among authors: scharow a.
Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4758-63. doi: 10.1002/anie.201410672. Epub 2015 Feb 20.
Angew Chem Int Ed Engl. 2015.
PMID: 25702814
Free PMC article.
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