Schelbergen RF - Search Results

1

Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis.

Schelbergen RF, de Munter W, van den Bosch MH, Lafeber FP, Sloetjes A, Vogl T, Roth J, van den Berg WB, van der Kraan PM, Blom AB, van Lent PL. Schelbergen RF, et al. Ann Rheum Dis. 2016 Jan;75(1):218-25. doi: 10.1136/annrheumdis-2014-205480. Epub 2014 Sep 1. Ann Rheum Dis. 2016. PMID: 25180294

2

Alarmin S100A9 Induces Proinflammatory and Catabolic Effects Predominantly in the M1 Macrophages of Human Osteoarthritic Synovium.

van den Bosch MH, Blom AB, Schelbergen RF, Koenders MI, van de Loo FA, van den Berg WB, Vogl T, Roth J, van der Kraan PM, van Lent PL. van den Bosch MH, et al. Among authors: schelbergen rf. J Rheumatol. 2016 Oct;43(10):1874-1884. doi: 10.3899/jrheum.160270. Epub 2016 Aug 1. J Rheumatol. 2016. PMID: 27481901

3

Treatment efficacy of adipose-derived stem cells in experimental osteoarthritis is driven by high synovial activation and reflected by S100A8/A9 serum levels.

Schelbergen RF, van Dalen S, ter Huurne M, Roth J, Vogl T, Noël D, Jorgensen C, van den Berg WB, van de Loo FA, Blom AB, van Lent PL. Schelbergen RF, et al. Osteoarthritis Cartilage. 2014 Aug;22(8):1158-66. doi: 10.1016/j.joca.2014.05.022. Epub 2014 Jun 10. Osteoarthritis Cartilage. 2014. PMID: 24928317 Free article.

4

Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.

Schelbergen RF, Geven EJ, van den Bosch MH, Eriksson H, Leanderson T, Vogl T, Roth J, van de Loo FA, Koenders MI, van der Kraan PM, van den Berg WB, Blom AB, van Lent PL. Schelbergen RF, et al. Ann Rheum Dis. 2015 Dec;74(12):2254-8. doi: 10.1136/annrheumdis-2014-206517. Epub 2015 May 12. Ann Rheum Dis. 2015. PMID: 25969431

5

Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4.

Schelbergen RF, Blom AB, van den Bosch MH, Slöetjes A, Abdollahi-Roodsaz S, Schreurs BW, Mort JS, Vogl T, Roth J, van den Berg WB, van Lent PL. Schelbergen RF, et al. Arthritis Rheum. 2012 May;64(5):1477-87. doi: 10.1002/art.33495. Arthritis Rheum. 2012. PMID: 22127564 Free article.

6

Active involvement of alarmins S100A8 and S100A9 in the regulation of synovial activation and joint destruction during mouse and human osteoarthritis.

van Lent PL, Blom AB, Schelbergen RF, Slöetjes A, Lafeber FP, Lems WF, Cats H, Vogl T, Roth J, van den Berg WB. van Lent PL, et al. Among authors: schelbergen rf. Arthritis Rheum. 2012 May;64(5):1466-76. doi: 10.1002/art.34315. Arthritis Rheum. 2012. PMID: 22143922 Free article.

7

Induction of Canonical Wnt Signaling by the Alarmins S100A8/A9 in Murine Knee Joints: Implications for Osteoarthritis.

van den Bosch MH, Blom AB, Schelbergen RF, Vogl T, Roth JP, Slöetjes AW, van den Berg WB, van der Kraan PM, van Lent PL. van den Bosch MH, et al. Among authors: schelbergen rf. Arthritis Rheumatol. 2016 Jan;68(1):152-63. doi: 10.1002/art.39420. Arthritis Rheumatol. 2016. PMID: 26360647

8

S100A8 causes a shift toward expression of activatory Fcγ receptors on macrophages via toll-like receptor 4 and regulates Fcγ receptor expression in synovium during chronic experimental arthritis.

van Lent PL, Grevers LC, Schelbergen R, Blom A, Geurts J, Sloetjes A, Vogl T, Roth J, van den Berg WB. van Lent PL, et al. Arthritis Rheum. 2010 Nov;62(11):3353-64. doi: 10.1002/art.27654. Arthritis Rheum. 2010. PMID: 20662072 Free article.

9

Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis.

ter Huurne M, Schelbergen R, Blattes R, Blom A, de Munter W, Grevers LC, Jeanson J, Noël D, Casteilla L, Jorgensen C, van den Berg W, van Lent PL. ter Huurne M, et al. Arthritis Rheum. 2012 Nov;64(11):3604-13. doi: 10.1002/art.34626. Arthritis Rheum. 2012. PMID: 22961401 Free article.

10

Liposomal targeting of prednisolone phosphate to synovial lining macrophages during experimental arthritis inhibits M1 activation but does not favor M2 differentiation.

Hofkens W, Schelbergen R, Storm G, van den Berg WB, van Lent PL. Hofkens W, et al. PLoS One. 2013;8(2):e54016. doi: 10.1371/journal.pone.0054016. Epub 2013 Feb 28. PLoS One. 2013. PMID: 23468840 Free PMC article.

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