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Early Aβ reduction prevents progression of cerebral amyloid angiopathy.
Schelle J, Wegenast-Braun BM, Fritschi SK, Kaeser SA, Jährling N, Eicke D, Skodras A, Beschorner N, Obermueller U, Häsler LM, Wolfer DP, Mueggler T, Shimshek DR, Neumann U, Dodt HU, Staufenbiel M, Jucker M. Schelle J, et al. Ann Neurol. 2019 Oct;86(4):561-571. doi: 10.1002/ana.25562. Epub 2019 Aug 19. Ann Neurol. 2019. PMID: 31359452
Persistence of Aβ seeds in APP null mouse brain.
Ye L, Fritschi SK, Schelle J, Obermüller U, Degenhardt K, Kaeser SA, Eisele YS, Walker LC, Baumann F, Staufenbiel M, Jucker M. Ye L, et al. Among authors: schelle j. Nat Neurosci. 2015 Nov;18(11):1559-61. doi: 10.1038/nn.4117. Epub 2015 Sep 9. Nat Neurosci. 2015. PMID: 26352792
Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice.
Shimshek DR, Jacobson LH, Kolly C, Zamurovic N, Balavenkatraman KK, Morawiec L, Kreutzer R, Schelle J, Jucker M, Bertschi B, Theil D, Heier A, Bigot K, Beltz K, Machauer R, Brzak I, Perrot L, Neumann U. Shimshek DR, et al. Among authors: schelle j. Sci Rep. 2016 Feb 25;6:21917. doi: 10.1038/srep21917. Sci Rep. 2016. PMID: 26912421 Free PMC article.
Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases.
Bacioglu M, Maia LF, Preische O, Schelle J, Apel A, Kaeser SA, Schweighauser M, Eninger T, Lambert M, Pilotto A, Shimshek DR, Neumann U, Kahle PJ, Staufenbiel M, Neumann M, Maetzler W, Kuhle J, Jucker M. Bacioglu M, et al. Among authors: schelle j. Neuron. 2016 Jul 6;91(1):56-66. doi: 10.1016/j.neuron.2016.05.018. Epub 2016 Jun 9. Neuron. 2016. PMID: 27292537 Free article.
Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases.
Bacioglu M, Maia LF, Preische O, Schelle J, Apel A, Kaeser SA, Schweighauser M, Eninger T, Lambert M, Pilotto A, Shimshek DR, Neumann U, Kahle PJ, Staufenbiel M, Neumann M, Maetzler W, Kuhle J, Jucker M. Bacioglu M, et al. Among authors: schelle j. Neuron. 2016 Jul 20;91(2):494-496. doi: 10.1016/j.neuron.2016.07.007. Epub 2016 Jul 20. Neuron. 2016. PMID: 27477021 Free article. No abstract available.
Aβ seeding potency peaks in the early stages of cerebral β-amyloidosis.
Ye L, Rasmussen J, Kaeser SA, Marzesco AM, Obermüller U, Mahler J, Schelle J, Odenthal J, Krüger C, Fritschi SK, Walker LC, Staufenbiel M, Baumann F, Jucker M. Ye L, et al. Among authors: schelle j. EMBO Rep. 2017 Sep;18(9):1536-1544. doi: 10.15252/embr.201744067. Epub 2017 Jul 12. EMBO Rep. 2017. PMID: 28701326 Free PMC article.
Infectious prions do not induce Aβ deposition in an in vivo seeding model.
Rasmussen J, Krasemann S, Altmeppen H, Schwarz P, Schelle J, Aguzzi A, Glatzel M, Jucker M. Rasmussen J, et al. Among authors: schelle j. Acta Neuropathol. 2018 Jun;135(6):965-967. doi: 10.1007/s00401-018-1848-5. Epub 2018 Apr 16. Acta Neuropathol. 2018. PMID: 29663066 No abstract available.
13 results