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Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.
Oppelt A, Kaschek D, Huppelschoten S, Sison-Young R, Zhang F, Buck-Wiese M, Herrmann F, Malkusch S, Krüger CL, Meub M, Merkt B, Zimmermann L, Schofield A, Jones RP, Malik H, Schilling M, Heilemann M, van de Water B, Goldring CE, Park BK, Timmer J, Klingmüller U. Oppelt A, et al. Among authors: schilling m. NPJ Syst Biol Appl. 2018 Jun 11;4:23. doi: 10.1038/s41540-018-0058-z. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29900006 Free PMC article.
Standardizing experimental protocols.
Schilling M, Pfeifer AC, Bohl S, Klingmüller U. Schilling M, et al. Curr Opin Biotechnol. 2008 Aug;19(4):354-9. doi: 10.1016/j.copbio.2008.06.007. Epub 2008 Jul 19. Curr Opin Biotechnol. 2008. PMID: 18617004 Review.
Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets.
Raia V, Schilling M, Böhm M, Hahn B, Kowarsch A, Raue A, Sticht C, Bohl S, Saile M, Möller P, Gretz N, Timmer J, Theis F, Lehmann WD, Lichter P, Klingmüller U. Raia V, et al. Among authors: schilling m. Cancer Res. 2011 Feb 1;71(3):693-704. doi: 10.1158/0008-5472.CAN-10-2987. Epub 2010 Dec 2. Cancer Res. 2011. PMID: 21127196
Predictive mathematical models of cancer signalling pathways.
Bachmann J, Raue A, Schilling M, Becker V, Timmer J, Klingmüller U. Bachmann J, et al. Among authors: schilling m. J Intern Med. 2012 Feb;271(2):155-65. doi: 10.1111/j.1365-2796.2011.02492.x. J Intern Med. 2012. PMID: 22142263 Free article. Review.
808 results