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Crowdsourced mapping of unexplored target space of kinase inhibitors.
Cichońska A, Ravikumar B, Allaway RJ, Wan F, Park S, Isayev O, Li S, Mason M, Lamb A, Tanoli Z, Jeon M, Kim S, Popova M, Capuzzi S, Zeng J, Dang K, Koytiger G, Kang J, Wells CI, Willson TM; IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium; Oprea TI, Schlessinger A, Drewry DH, Stolovitzky G, Wennerberg K, Guinney J, Aittokallio T. Cichońska A, et al. Among authors: schlessinger a. Nat Commun. 2021 Jun 3;12(1):3307. doi: 10.1038/s41467-021-23165-1. Nat Commun. 2021. PMID: 34083538 Free PMC article.
Multi-targeting Drug Community Challenge.
Schlessinger A, Abagyan R, Carlson HA, Dang KK, Guinney J, Cagan RL. Schlessinger A, et al. Cell Chem Biol. 2017 Dec 21;24(12):1434-1435. doi: 10.1016/j.chembiol.2017.12.006. Cell Chem Biol. 2017. PMID: 29272700 Free article. No abstract available.
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity.
van Hasselt JGC, Rahman R, Hansen J, Stern A, Shim JV, Xiong Y, Pickard A, Jayaraman G, Hu B, Mahajan M, Gallo JM, Goldfarb J, Sobie EA, Birtwistle MR, Schlessinger A, Azeloglu EU, Iyengar R. van Hasselt JGC, et al. Among authors: schlessinger a. Nat Commun. 2020 Sep 23;11(1):4809. doi: 10.1038/s41467-020-18396-7. Nat Commun. 2020. PMID: 32968055 Free PMC article.
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge.
Xiong Z, Jeon M, Allaway RJ, Kang J, Park D, Lee J, Jeon H, Ko M, Jiang H, Zheng M, Tan AC, Guo X; Multi-Targeting Drug DREAM Challenge Community; Dang KK, Tropsha A, Hecht C, Das TK, Carlson HA, Abagyan R, Guinney J, Schlessinger A, Cagan R. Xiong Z, et al. Among authors: schlessinger a. PLoS Comput Biol. 2021 Sep 14;17(9):e1009302. doi: 10.1371/journal.pcbi.1009302. eCollection 2021 Sep. PLoS Comput Biol. 2021. PMID: 34520464 Free PMC article.
110 results