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Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket.
Schmidt EN, Lamprinaki D, McCord KA, Joe M, Sojitra M, Waldow A, Nguyen J, Monyror J, Kitova EN, Mozaneh F, Guo XY, Jung J, Enterina JR, Daskhan GC, Han L, Krysler AR, Cromwell CR, Hubbard BP, West LJ, Kulka M, Sipione S, Klassen JS, Derda R, Lowary TL, Mahal LK, Riddell MR, Macauley MS. Schmidt EN, et al. Nat Commun. 2023 Apr 22;14(1):2327. doi: 10.1038/s41467-023-38030-6. Nat Commun. 2023. PMID: 37087495 Free PMC article.
Flow Cytometry-Based Detection of Siglec Ligands.
Schmidt EN, Jung J, Macauley MS. Schmidt EN, et al. Methods Mol Biol. 2023;2657:181-193. doi: 10.1007/978-1-0716-3151-5_13. Methods Mol Biol. 2023. PMID: 37149531
Absolute Affinities from Quantitative Shotgun Glycomics Using Concentration-Independent (COIN) Native Mass Spectrometry.
Bui DT, Favell J, Kitova EN, Li Z, McCord KA, Schmidt EN, Mozaneh F, Elaish M, El-Hawiet A, St-Pierre Y, Hobman TC, Macauley MS, Mahal LK, Flynn MR, Klassen JS. Bui DT, et al. Among authors: schmidt en. ACS Cent Sci. 2023 Jun 15;9(7):1374-1387. doi: 10.1021/acscentsci.3c00294. eCollection 2023 Jul 26. ACS Cent Sci. 2023. PMID: 37521792 Free PMC article.
A thicker skin for better immune evasion.
Schmidt EN, Macauley MS. Schmidt EN, et al. Nat Mater. 2024 Mar;23(3):312-313. doi: 10.1038/s41563-024-01822-2. Nat Mater. 2024. PMID: 38438619 No abstract available.
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer.
Garnham R, Geh D, Nelson R, Ramon-Gil E, Wilson L, Schmidt EN, Walker L, Adamson B, Buskin A, Hepburn AC, Hodgson K, Kendall H, Frame FM, Maitland N, Coffey K, Strand DW, Robson CN, Elliott DJ, Heer R, Macauley M, Munkley J, Gaughan L, Leslie J, Scott E. Garnham R, et al. Among authors: schmidt en. Commun Biol. 2024 Mar 6;7(1):276. doi: 10.1038/s42003-024-05924-0. Commun Biol. 2024. PMID: 38448753 Free PMC article.
The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis.
Rice K, Batul K, Whiteside J, Kelso J, Papinski M, Schmidt E, Pratasouskaya A, Wang D, Sullivan R, Bartlett C, Weadge JT, Van der Kamp MW, Moreno-Hagelsieb G, Suits MD, Horsman GP. Rice K, et al. Nat Commun. 2019 Aug 16;10(1):3698. doi: 10.1038/s41467-019-11627-6. Nat Commun. 2019. PMID: 31420548 Free PMC article.
Anti-inflammatory role of GM1 and other gangliosides on microglia.
Galleguillos D, Wang Q, Steinberg N, Zaidi A, Shrivastava G, Dhami K, Daskhan GC, Schmidt EN, Dworsky-Fried Z, Giuliani F, Churchward M, Power C, Todd K, Taylor A, Macauley MS, Sipione S. Galleguillos D, et al. Among authors: schmidt en. J Neuroinflammation. 2022 Jan 6;19(1):9. doi: 10.1186/s12974-021-02374-x. J Neuroinflammation. 2022. PMID: 34991625 Free PMC article.
Inhibition of Intercellular Cytosolic Traffic via Gap Junctions Reinforces Lomustine-Induced Toxicity in Glioblastoma Independent of MGMT Promoter Methylation Status.
Schneider M, Potthoff AL, Evert BO, Dicks M, Ehrentraut D, Dolf A, Schmidt ENC, Schäfer N, Borger V, Pietsch T, Westhoff MA, Güresir E, Waha A, Vatter H, Heiland DH, Schuss P, Herrlinger U. Schneider M, et al. Among authors: schmidt enc. Pharmaceuticals (Basel). 2021 Feb 27;14(3):195. doi: 10.3390/ph14030195. Pharmaceuticals (Basel). 2021. PMID: 33673490 Free PMC article.
A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands.
Rodrigues E, Jung J, Park H, Loo C, Soukhtehzari S, Kitova EN, Mozaneh F, Daskhan G, Schmidt EN, Aghanya V, Sarkar S, Streith L, St Laurent CD, Nguyen L, Julien JP, West LJ, Williams KC, Klassen JS, Macauley MS. Rodrigues E, et al. Among authors: schmidt en. Nat Commun. 2020 Oct 9;11(1):5091. doi: 10.1038/s41467-020-18907-6. Nat Commun. 2020. PMID: 33037195 Free PMC article.
15 results