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TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.
Ma XR, Prudencio M, Koike Y, Vatsavayai SC, Kim G, Harbinski F, Briner A, Rodriguez CM, Guo C, Akiyama T, Schmidt HB, Cummings BB, Wyatt DW, Kurylo K, Miller G, Mekhoubad S, Sallee N, Mekonnen G, Ganser L, Rubien JD, Jansen-West K, Cook CN, Pickles S, Oskarsson B, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Shorter J, Myong S, Green EM, Seeley WW, Petrucelli L, Gitler AD. Ma XR, et al. Among authors: schmidt hb. Nature. 2022 Mar;603(7899):124-130. doi: 10.1038/s41586-022-04424-7. Epub 2022 Feb 23. Nature. 2022. PMID: 35197626 Free PMC article.
TDP-43 α-helical structure tunes liquid-liquid phase separation and function.
Conicella AE, Dignon GL, Zerze GH, Schmidt HB, D'Ordine AM, Kim YC, Rohatgi R, Ayala YM, Mittal J, Fawzi NL. Conicella AE, et al. Among authors: schmidt hb. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5883-5894. doi: 10.1073/pnas.1912055117. Epub 2020 Mar 4. Proc Natl Acad Sci U S A. 2020. PMID: 32132204 Free PMC article.
Aberrant Phase Separation of FUS Leads to Lysosome Sequestering and Acidification.
Trnka F, Hoffmann C, Wang H, Sansevrino R, Rankovic B, Rost BR, Schmitz D, Schmidt HB, Milovanovic D. Trnka F, et al. Among authors: schmidt hb. Front Cell Dev Biol. 2021 Oct 22;9:716919. doi: 10.3389/fcell.2021.716919. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34746121 Free PMC article.
Oxaliplatin disrupts nucleolar function through biophysical disintegration.
Schmidt HB, Jaafar ZA, Wulff BE, Rodencal JJ, Hong K, Aziz-Zanjani MO, Jackson PK, Leonetti MD, Dixon SJ, Rohatgi R, Brandman O. Schmidt HB, et al. Cell Rep. 2022 Nov 8;41(6):111629. doi: 10.1016/j.celrep.2022.111629. Cell Rep. 2022. PMID: 36351392 Free PMC article.
Direct ionic stress sensing and mitigation by the transcription factor NFAT5.
Khandwala CB, Sarkar P, Schmidt HB, Ma M, Kinnebrew M, Pusapati GV, Patel BB, Tillo D, Lebensohn AM, Rohatgi R. Khandwala CB, et al. Among authors: schmidt hb. bioRxiv [Preprint]. 2023 Sep 24:2023.09.23.559074. doi: 10.1101/2023.09.23.559074. bioRxiv. 2023. PMID: 37886503 Free PMC article. Preprint.
30 results