Schmitt-Hoffmann A - Search Results

1

New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine.

Angehrn P, Buchmann S, Funk C, Goetschi E, Gmuender H, Hebeisen P, Kostrewa D, Link H, Luebbers T, Masciadri R, Nielsen J, Reindl P, Ricklin F, Schmitt-Hoffmann A, Theil FP. Angehrn P, et al. J Med Chem. 2004 Mar 11;47(6):1487-513. doi: 10.1021/jm0310232. J Med Chem. 2004. PMID: 14998336

2

A new DNA gyrase inhibitor subclass of the cyclothialidine family based on a bicyclic dilactam-lactone scaffold. Synthesis and antibacterial properties.

Angehrn P, Goetschi E, Gmuender H, Hebeisen P, Hennig M, Kuhn B, Luebbers T, Reindl P, Ricklin F, Schmitt-Hoffmann A. Angehrn P, et al. J Med Chem. 2011 Apr 14;54(7):2207-24. doi: 10.1021/jm1014023. Epub 2011 Mar 9. J Med Chem. 2011. PMID: 21388139

3

Novel ketolide antibiotics with a fused five-membered lactone ring--synthesis, physicochemical and antimicrobial properties.

Hunziker D, Wyss PC, Angehrn P, Mueller A, Marty HP, Halm R, Kellenberger L, Bitsch V, Biringer G, Arnold W, Stämpfli A, Schmitt-Hoffmann A, Cousot D. Hunziker D, et al. Bioorg Med Chem. 2004 Jul 1;12(13):3503-19. doi: 10.1016/j.bmc.2004.04.039. Bioorg Med Chem. 2004. PMID: 15186835

4

Physiologically based pharmacokinetic (PBPK) modeling of disposition of epiroprim in humans.

Luttringer O, Theil FP, Poulin P, Schmitt-Hoffmann AH, Guentert TW, Lavé T. Luttringer O, et al. J Pharm Sci. 2003 Oct;92(10):1990-2007. doi: 10.1002/jps.10461. J Pharm Sci. 2003. PMID: 14502539

5

In vitro and in vivo properties of dihydrophthalazine antifolates, a novel family of antibacterial drugs.

Caspers P, Bury L, Gaucher B, Heim J, Shapiro S, Siegrist S, Schmitt-Hoffmann A, Thenoz L, Urwyler H. Caspers P, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3620-7. doi: 10.1128/AAC.00377-09. Epub 2009 Jun 22. Antimicrob Agents Chemother. 2009. PMID: 19546364 Free PMC article.

6

Combined effects of the siderophore monosulfactam BAL30072 and carbapenems on multidrug-resistant Gram-negative bacilli.

Hofer B, Dantier C, Gebhardt K, Desarbre E, Schmitt-Hoffmann A, Page MG. Hofer B, et al. J Antimicrob Chemother. 2013 May;68(5):1120-9. doi: 10.1093/jac/dks527. Epub 2013 Jan 22. J Antimicrob Chemother. 2013. PMID: 23344577

7

In vitro and in vivo properties of BAL30376, a β-lactam and dual beta-lactamase inhibitor combination with enhanced activity against Gram-negative Bacilli that express multiple β-lactamases.

Page MG, Dantier C, Desarbre E, Gaucher B, Gebhardt K, Schmitt-Hoffmann A. Page MG, et al. Antimicrob Agents Chemother. 2011 Apr;55(4):1510-9. doi: 10.1128/AAC.01370-10. Epub 2011 Jan 18. Antimicrob Agents Chemother. 2011. PMID: 21245441 Free PMC article.

8

Animal pharmacokinetics and interspecies scaling from animals to man of lamifiban, a new platelet aggregation inhibitor.

Lave T, Saner A, Coassolo P, Brandt R, Schmitt-Hoffmann AH, Chou RC. Lave T, et al. J Pharm Pharmacol. 1996 Jun;48(6):573-7. doi: 10.1111/j.2042-7158.1996.tb05976.x. J Pharm Pharmacol. 1996. PMID: 8832489

9

Interspecies scaling of interferon disposition and comparison of allometric scaling with concentration-time transformations.

Lave T, Levet-Trafit B, Schmitt-Hoffmann AH, Morgenroth B, Richter W, Chou RC. Lave T, et al. J Pharm Sci. 1995 Nov;84(11):1285-90. doi: 10.1002/jps.2600841106. J Pharm Sci. 1995. PMID: 8587044 Clinical Trial.

10

Elucidation of the in vitro metabolic profile of stable isotope labeled BAL19403 by accurate mass capillary liquid chromatography/quadrupole time-of-flight mass spectrometry and isotope exchange.

Wind M, Gebhardt K, Grunwald H, Spickermann J, Donzelli M, Kellenberger L, Muller M, Fullhardt P, Schmitt-Hoffmann A, Schleimer M. Wind M, et al. Rapid Commun Mass Spectrom. 2007;21(7):1093-9. doi: 10.1002/rcm.2926. Rapid Commun Mass Spectrom. 2007. PMID: 17318924

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