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IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation.
Faas M, Ipseiz N, Ackermann J, Culemann S, Grüneboom A, Schröder F, Rothe T, Scholtysek C, Eberhardt M, Böttcher M, Kirchner P, Stoll C, Ekici A, Fuchs M, Kunz M, Weigmann B, Wirtz S, Lang R, Hofmann J, Vera J, Voehringer D, Michelucci A, Mougiakakos D, Uderhardt S, Schett G, Krönke G. Faas M, et al. Among authors: scholtysek c. Immunity. 2021 Nov 9;54(11):2531-2546.e5. doi: 10.1016/j.immuni.2021.09.010. Epub 2021 Oct 12. Immunity. 2021. PMID: 34644537 Free article.
12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.
Krönke G, Katzenbeisser J, Uderhardt S, Zaiss MM, Scholtysek C, Schabbauer G, Zarbock A, Koenders MI, Axmann R, Zwerina J, Baenckler HW, van den Berg W, Voll RE, Kühn H, Joosten LA, Schett G. Krönke G, et al. Among authors: scholtysek c. J Immunol. 2009 Sep 1;183(5):3383-9. doi: 10.4049/jimmunol.0900327. Epub 2009 Aug 12. J Immunol. 2009. PMID: 19675173 Free article.
R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway.
Krönke G, Uderhardt S, Kim KA, Stock M, Scholtysek C, Zaiss MM, Surmann-Schmitt C, Luther J, Katzenbeisser J, David JP, Abdollahi-Roodsaz S, Tran K, Bright JM, Binnerts ME, Akhmetshina A, Böhm C, Distler JH, Joosten LA, Schett G, Abo A. Krönke G, et al. Among authors: scholtysek c. Arthritis Rheum. 2010 Aug;62(8):2303-12. doi: 10.1002/art.27496. Arthritis Rheum. 2010. PMID: 20506554 Free article.
IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss.
Zaiss MM, Kurowska-Stolarska M, Böhm C, Gary R, Scholtysek C, Stolarski B, Reilly J, Kerr S, Millar NL, Kamradt T, McInnes IB, Fallon PG, David JP, Liew FY, Schett G. Zaiss MM, et al. Among authors: scholtysek c. J Immunol. 2011 Jun 1;186(11):6097-105. doi: 10.4049/jimmunol.1003487. Epub 2011 Apr 22. J Immunol. 2011. PMID: 21515798
Inflammation-associated changes in bone homeostasis.
Scholtysek C, Krönke G, Schett G. Scholtysek C, et al. Inflamm Allergy Drug Targets. 2012 Jun;11(3):188-95. doi: 10.2174/187152812800392706. Inflamm Allergy Drug Targets. 2012. PMID: 22280240 Review.
RSK2 protects mice against TNF-induced bone loss.
Böhm C, Derer A, Axmann R, Hillienhoff U, Zaiss MM, Luther J, Zech C, Stock M, Scholtysek C, Engelke K, Hess A, Tuckermann JP, Schett G, David JP. Böhm C, et al. Among authors: scholtysek c. J Cell Sci. 2012 May 1;125(Pt 9):2160-71. doi: 10.1242/jcs.096008. Epub 2012 Feb 17. J Cell Sci. 2012. PMID: 22344264
Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.
Lin NY, Beyer C, Giessl A, Kireva T, Scholtysek C, Uderhardt S, Munoz LE, Dees C, Distler A, Wirtz S, Krönke G, Spencer B, Distler O, Schett G, Distler JH. Lin NY, et al. Among authors: scholtysek c. Ann Rheum Dis. 2013 May;72(5):761-8. doi: 10.1136/annrheumdis-2012-201671. Epub 2012 Sep 12. Ann Rheum Dis. 2013. PMID: 22975756
PPARβ/δ governs Wnt signaling and bone turnover.
Scholtysek C, Katzenbeisser J, Fu H, Uderhardt S, Ipseiz N, Stoll C, Zaiss MM, Stock M, Donhauser L, Böhm C, Kleyer A, Hess A, Engelke K, David JP, Djouad F, Tuckermann JP, Desvergne B, Schett G, Krönke G. Scholtysek C, et al. Nat Med. 2013 May;19(5):608-13. doi: 10.1038/nm.3146. Epub 2013 Mar 31. Nat Med. 2013. PMID: 23542786
26 results