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An isoform-specific C/EBPβ inhibitor targets acute myeloid leukemia cells.
Jakobs A, Uttarkar S, Schomburg C, Steinmann S, Coulibaly A, Schlenke P, Berdel WE, Müller-Tidow C, Schmidt TJ, Klempnauer KH. Jakobs A, et al. Among authors: schomburg c. Leukemia. 2016 Jul;30(7):1612-5. doi: 10.1038/leu.2016.16. Epub 2016 Feb 8. Leukemia. 2016. PMID: 26854027 No abstract available.
Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction.
Uttarkar S, Dassé E, Coulibaly A, Steinmann S, Jakobs A, Schomburg C, Trentmann A, Jose J, Schlenke P, Berdel WE, Schmidt TJ, Müller-Tidow C, Frampton J, Klempnauer KH. Uttarkar S, et al. Among authors: schomburg c. Blood. 2016 Mar 3;127(9):1173-82. doi: 10.1182/blood-2015-09-668632. Epub 2015 Dec 2. Blood. 2016. PMID: 26631113 Free article.
Withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPβ.
Falkenberg KD, Jakobs A, Matern JC, Dörner W, Uttarkar S, Trentmann A, Steinmann S, Coulibaly A, Schomburg C, Mootz HD, Schmidt TJ, Klempnauer KH. Falkenberg KD, et al. Among authors: schomburg c. Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1349-1358. doi: 10.1016/j.bbamcr.2017.05.003. Epub 2017 May 2. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28476645 Free article.
15 results