Schopfer U - Search Results

1

How Phenotypic Screening Influenced Drug Discovery: Lessons from Five Years of Practice.

Haasen D, Schopfer U, Antczak C, Guy C, Fuchs F, Selzer P. Haasen D, et al. Among authors: schopfer u. Assay Drug Dev Technol. 2017 Aug/Sep;15(6):239-246. doi: 10.1089/adt.2017.796. Epub 2017 Aug 11. Assay Drug Dev Technol. 2017. PMID: 28800248 Review.

2

Key aspects of the Novartis compound collection enhancement project for the compilation of a comprehensive chemogenomics drug discovery screening collection.

Jacoby E, Schuffenhauer A, Popov M, Azzaoui K, Havill B, Schopfer U, Engeloch C, Stanek J, Acklin P, Rigollier P, Stoll F, Koch G, Meier P, Orain D, Giger R, Hinrichs J, Malagu K, Zimmermann J, Roth HJ. Jacoby E, et al. Among authors: schopfer u. Curr Top Med Chem. 2005;5(4):397-411. doi: 10.2174/1568026053828376. Curr Top Med Chem. 2005. PMID: 15892682 Review.

3

Hypothesis-driven screening.

Schopfer U, Engeloch C, Höhn F, Mees H, Leeds J, Glickman F, Scheel G, Ferrand S, Fekkes P, Pfeifer M. Schopfer U, et al. Methods Mol Biol. 2009;575:297-316. doi: 10.1007/978-1-60761-274-2_13. Methods Mol Biol. 2009. PMID: 19727621

4

Molecular diversity management strategies for building and enhancement of diverse and focused lead discovery compound screening collections.

Schuffenhauer A, Popov M, Schopfer U, Acklin P, Stanek J, Jacoby E. Schuffenhauer A, et al. Among authors: schopfer u. Comb Chem High Throughput Screen. 2004 Dec;7(8):771-81. doi: 10.2174/1386207043328238. Comb Chem High Throughput Screen. 2004. PMID: 15578939 Review.

5

Compound Hub: efficiency gains through innovative sample management processes.

Schopfer U, Andreae MR, Hueber M, Saur A, Kummer MO, Girod M, Fox D, Steiner T, Popov M, Smith R. Schopfer U, et al. Comb Chem High Throughput Screen. 2007 May;10(4):283-7. doi: 10.2174/138620707780636655. Comb Chem High Throughput Screen. 2007. PMID: 17506712

6

Screening library evolution through automation of solution preparation.

Schopfer U, Höhn F, Hueber M, Girod M, Engeloch C, Popov M, Muckenschnabel I. Schopfer U, et al. J Biomol Screen. 2007 Aug;12(5):724-32. doi: 10.1177/1087057107301939. Epub 2007 May 16. J Biomol Screen. 2007. PMID: 17507640

7

Knowledge-based virtual screening: application to the MDM4/p53 protein-protein interaction.

Jacoby E, Boettcher A, Mayr LM, Brown N, Jenkins JL, Kallen J, Engeloch C, Schopfer U, Furet P, Masuya K, Lisztwan J. Jacoby E, et al. Among authors: schopfer u. Methods Mol Biol. 2009;575:173-94. doi: 10.1007/978-1-60761-274-2_7. Methods Mol Biol. 2009. PMID: 19727615

8

HDL-like discs for assaying membrane proteins in drug discovery.

Fiez-Vandal C, Leder L, Freuler F, Sykes D, Charlton SJ, Siehler S, Schopfer U, Duckely M. Fiez-Vandal C, et al. Among authors: schopfer u. Biophys Chem. 2012 May;165-166:56-61. doi: 10.1016/j.bpc.2012.03.005. Epub 2012 Mar 19. Biophys Chem. 2012. PMID: 22542136

9

High-Throughput Screening Using iPSC-Derived Neuronal Progenitors to Identify Compounds Counteracting Epigenetic Gene Silencing in Fragile X Syndrome.

Kaufmann M, Schuffenhauer A, Fruh I, Klein J, Thiemeyer A, Rigo P, Gomez-Mancilla B, Heidinger-Millot V, Bouwmeester T, Schopfer U, Mueller M, Fodor BD, Cobos-Correa A. Kaufmann M, et al. Among authors: schopfer u. J Biomol Screen. 2015 Oct;20(9):1101-11. doi: 10.1177/1087057115588287. Epub 2015 May 29. J Biomol Screen. 2015. PMID: 26024946

10

Theoretical and experimental relationships between percent inhibition and IC50 data observed in high-throughput screening.

Gubler H, Schopfer U, Jacoby E. Gubler H, et al. Among authors: schopfer u. J Biomol Screen. 2013 Jan;18(1):1-13. doi: 10.1177/1087057112455219. Epub 2012 Aug 1. J Biomol Screen. 2013. PMID: 22853931

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