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Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects.
Schäcke H, Schottelius A, Döcke WD, Strehlke P, Jaroch S, Schmees N, Rehwinkel H, Hennekes H, Asadullah K. Schäcke H, et al. Among authors: schottelius a. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):227-32. doi: 10.1073/pnas.0300372101. Epub 2003 Dec 23. Proc Natl Acad Sci U S A. 2004. PMID: 14694204 Free PMC article.
SEGRAs: a novel class of anti-inflammatory compounds.
Schäcke H, Hennekes H, Schottelius A, Jaroch S, Lehmann M, Schmees N, Rehwinkel H, Asadullah K. Schäcke H, et al. Among authors: schottelius a. Ernst Schering Res Found Workshop. 2002;(40):357-71. doi: 10.1007/978-3-662-04660-9_20. Ernst Schering Res Found Workshop. 2002. PMID: 12355726 Review.
29 results