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New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation.
Pandolfi F, De Vita D, Bortolami M, Coluccia A, Di Santo R, Costi R, Andrisano V, Alabiso F, Bergamini C, Fato R, Bartolini M, Scipione L. Pandolfi F, et al. Among authors: scipione l. Eur J Med Chem. 2017 Dec 1;141:197-210. doi: 10.1016/j.ejmech.2017.09.022. Epub 2017 Sep 18. Eur J Med Chem. 2017. PMID: 29031067
Simple choline esters as potential anti-Alzheimer agents.
Alcaro S, Arcone R, Costa G, De Vita D, Iannone M, Ortuso F, Procopio A, Pasceri R, Rotiroti D, Scipione L. Alcaro S, et al. Among authors: scipione l. Curr Pharm Des. 2010;16(6):692-7. doi: 10.2174/138161210790883796. Curr Pharm Des. 2010. PMID: 20388079
Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents.
Friggeri L, Ballante F, Ragno R, Musmuca I, De Vita D, Manetti F, Biava M, Scipione L, Di Santo R, Costi R, Feroci M, Tortorella S. Friggeri L, et al. Among authors: scipione l. J Chem Inf Model. 2013 Jun 24;53(6):1463-74. doi: 10.1021/ci400132q. Epub 2013 May 17. J Chem Inf Model. 2013. PMID: 23617317
New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
Costi R, Crucitti GC, Pescatori L, Messore A, Scipione L, Tortorella S, Amoroso A, Crespan E, Campiglia P, Maresca B, Porta A, Granata I, Novellino E, Gouge J, Delarue M, Maga G, Di Santo R. Costi R, et al. Among authors: scipione l. J Med Chem. 2013 Sep 26;56(18):7431-41. doi: 10.1021/jm4010187. Epub 2013 Sep 12. J Med Chem. 2013. PMID: 23968551
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach.
Costi R, Métifiot M, Esposito F, Cuzzucoli Crucitti G, Pescatori L, Messore A, Scipione L, Tortorella S, Zinzula L, Novellino E, Pommier Y, Tramontano E, Marchand C, Di Santo R. Costi R, et al. Among authors: scipione l. J Med Chem. 2013 Nov 14;56(21):8588-98. doi: 10.1021/jm401040b. Epub 2013 Nov 5. J Med Chem. 2013. PMID: 24124919 Free PMC article.
Activity of caffeic acid derivatives against Candida albicans biofilm.
De Vita D, Friggeri L, D'Auria FD, Pandolfi F, Piccoli F, Panella S, Palamara AT, Simonetti G, Scipione L, Di Santo R, Costi R, Tortorella S. De Vita D, et al. Among authors: scipione l. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1502-5. doi: 10.1016/j.bmcl.2014.02.005. Epub 2014 Feb 13. Bioorg Med Chem Lett. 2014. PMID: 24582984
67 results