Scott GS - Search Results

1

The role of uric acid in protection against peroxynitrite-mediated pathology.

Scott GS, Hooper DC. Scott GS, et al. Med Hypotheses. 2001 Jan;56(1):95-100. doi: 10.1054/mehy.2000.1118. Med Hypotheses. 2001. PMID: 11133262

2

Comparison of uric acid and ascorbic acid in protection against EAE.

Spitsin SV, Scott GS, Mikheeva T, Zborek A, Kean RB, Brimer CM, Koprowski H, Hooper DC. Spitsin SV, et al. Among authors: scott gs. Free Radic Biol Med. 2002 Nov 15;33(10):1363-71. doi: 10.1016/s0891-5849(02)01048-1. Free Radic Biol Med. 2002. PMID: 12419468

3

Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors.

Scott GS, Spitsin SV, Kean RB, Mikheeva T, Koprowski H, Hooper DC. Scott GS, et al. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16303-8. doi: 10.1073/pnas.212645999. Epub 2002 Nov 25. Proc Natl Acad Sci U S A. 2002. PMID: 12451183 Free PMC article.

4

Uric acid protects against secondary damage after spinal cord injury.

Scott GS, Cuzzocrea S, Genovese T, Koprowski H, Hooper DC. Scott GS, et al. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3483-8. doi: 10.1073/pnas.0500307102. Epub 2005 Feb 22. Proc Natl Acad Sci U S A. 2005. PMID: 15728348 Free PMC article.

5

The central nervous system inflammatory response to neurotropic virus infection is peroxynitrite dependent.

Hooper DC, Kean RB, Scott GS, Spitsin SV, Mikheeva T, Morimoto K, Bette M, Röhrenbeck AM, Dietzschold B, Weihe E. Hooper DC, et al. Among authors: scott gs. J Immunol. 2001 Sep 15;167(6):3470-7. doi: 10.4049/jimmunol.167.6.3470. J Immunol. 2001. PMID: 11544340

6

Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis.

Hooper DC, Scott GS, Zborek A, Mikheeva T, Kean RB, Koprowski H, Spitsin SV. Hooper DC, et al. Among authors: scott gs. FASEB J. 2000 Apr;14(5):691-8. doi: 10.1096/fasebj.14.5.691. FASEB J. 2000. PMID: 10744626

7

Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid.

Spitsin SV, Scott GS, Kean RB, Mikheeva T, Hooper DC. Spitsin SV, et al. Among authors: scott gs. Neurosci Lett. 2000 Oct 6;292(2):137-41. doi: 10.1016/s0304-3940(00)01446-4. Neurosci Lett. 2000. PMID: 10998568

8

The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis through maintenance of blood-central nervous system barrier integrity.

Kean RB, Spitsin SV, Mikheeva T, Scott GS, Hooper DC. Kean RB, et al. Among authors: scott gs. J Immunol. 2000 Dec 1;165(11):6511-8. doi: 10.4049/jimmunol.165.11.6511. J Immunol. 2000. PMID: 11086092

9

Peroxynitrite-induced oligodendrocyte toxicity is not dependent on poly(ADP-ribose) polymerase activation.

Scott GS, Virág L, Szabó C, Hooper DC. Scott GS, et al. Glia. 2003 Jan 15;41(2):105-16. doi: 10.1002/glia.10137. Glia. 2003. PMID: 12509801

10

The therapeutic effects of PJ34 [N-(6-oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a selective inhibitor of poly(ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation.

Scott GS, Kean RB, Mikheeva T, Fabis MJ, Mabley JG, Szabó C, Hooper DC. Scott GS, et al. J Pharmacol Exp Ther. 2004 Sep;310(3):1053-61. doi: 10.1124/jpet.103.063214. Epub 2004 May 24. J Pharmacol Exp Ther. 2004. PMID: 15159442

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