Segal RA - Search Results

1

A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.

Hwang GH, Pazyra-Murphy MF, Seo HS, Dhe-Paganon S, Stopka SA, DiPiazza M, Sutter N, Gero TW, Volkert A, Ombelets L, Dittemore G, Rees MG, Ronan MM, Roth JA, Agar NYR, Scott DA, Segal RA. Hwang GH, et al. Among authors: segal ra. Cancer Res. 2024 Mar 15;84(6):872-886. doi: 10.1158/0008-5472.CAN-22-3784. Cancer Res. 2024. PMID: 38486486

2

A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma.

Pak E, MacKenzie EL, Zhao X, Pazyra-Murphy MF, Park PMC, Wu L, Shaw DL, Addleson EC, Cayer SS, Lopez BG, Agar NYR, Rubin LL, Qi J, Merk DJ, Segal RA. Pak E, et al. Among authors: segal ra. Neuro Oncol. 2019 Sep 6;21(9):1150-1163. doi: 10.1093/neuonc/noz089. Neuro Oncol. 2019. PMID: 31111916 Free PMC article.

3

An Architect of the Hindbrain: DDX3X Regulates Normal and Malignant Development.

Hwang GH, Segal RA. Hwang GH, et al. Among authors: segal ra. Dev Cell. 2020 Aug 24;54(4):425-426. doi: 10.1016/j.devcel.2020.07.021. Dev Cell. 2020. PMID: 32841591 Free article.

4

A Transposon Screen Identifies Loss of Primary Cilia as a Mechanism of Resistance to SMO Inhibitors.

Zhao X, Pak E, Ornell KJ, Pazyra-Murphy MF, MacKenzie EL, Chadwick EJ, Ponomaryov T, Kelleher JF, Segal RA. Zhao X, et al. Among authors: segal ra. Cancer Discov. 2017 Dec;7(12):1436-1449. doi: 10.1158/2159-8290.CD-17-0281. Epub 2017 Sep 18. Cancer Discov. 2017. PMID: 28923910

5

The Eya1 Phosphatase Mediates Shh-Driven Symmetric Cell Division of Cerebellar Granule Cell Precursors.

Merk DJ, Zhou P, Cohen SM, Pazyra-Murphy MF, Hwang GH, Rehm KJ, Alfaro J, Reid CM, Zhao X, Park E, Xu PX, Chan JA, Eck MJ, Nazemi KJ, Harwell CC, Segal RA. Merk DJ, et al. Among authors: segal ra. Dev Neurosci. 2020;42(5-6):170-186. doi: 10.1159/000512976. Epub 2021 Jan 20. Dev Neurosci. 2020. PMID: 33472197 Free PMC article.

6

Preparation and maintenance of dorsal root ganglia neurons in compartmented cultures.

Pazyra-Murphy MF, Segal RA. Pazyra-Murphy MF, et al. Among authors: segal ra. J Vis Exp. 2008 Oct 17;(20):951. doi: 10.3791/951. J Vis Exp. 2008. PMID: 19078939 Free PMC article.

7

Shh-proteoglycan interactions regulate maturation of olfactory glomerular circuitry.

Persson L, Witt RM, Galligan M, Greer PL, Eisner A, Pazyra-Murphy MF, Datta SR, Segal RA. Persson L, et al. Among authors: segal ra. Dev Neurobiol. 2014 Dec;74(12):1255-67. doi: 10.1002/dneu.22202. Epub 2014 Jun 27. Dev Neurobiol. 2014. PMID: 24913191 Free PMC article.

8

The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.

Eisner A, Pazyra-Murphy MF, Durresi E, Zhou P, Zhao X, Chadwick EC, Xu PX, Hillman RT, Scott MP, Greenberg ME, Segal RA. Eisner A, et al. Among authors: segal ra. Dev Cell. 2015 Apr 6;33(1):22-35. doi: 10.1016/j.devcel.2015.01.033. Epub 2015 Mar 26. Dev Cell. 2015. PMID: 25816987 Free PMC article.

9

Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses.

Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA. Chan JA, et al. Among authors: segal ra. Nat Neurosci. 2009 Apr;12(4):409-17. doi: 10.1038/nn.2287. Epub 2009 Mar 15. Nat Neurosci. 2009. PMID: 19287388 Free PMC article.

10

Sensory neuropathy attributable to loss of Bcl-w.

Courchesne SL, Karch C, Pazyra-Murphy MF, Segal RA. Courchesne SL, et al. Among authors: segal ra. J Neurosci. 2011 Feb 2;31(5):1624-34. doi: 10.1523/JNEUROSCI.3347-10.2011. J Neurosci. 2011. PMID: 21289171 Free PMC article.

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