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Beneficial effects of exendin-4 on experimental polyneuropathy in diabetic mice.
Himeno T, Kamiya H, Naruse K, Harada N, Ozaki N, Seino Y, Shibata T, Kondo M, Kato J, Okawa T, Fukami A, Hamada Y, Inagaki N, Seino Y, Drucker DJ, Oiso Y, Nakamura J. Himeno T, et al. Among authors: seino y. Diabetes. 2011 Sep;60(9):2397-406. doi: 10.2337/db10-1462. Epub 2011 Aug 1. Diabetes. 2011. PMID: 21810596 Free PMC article.
Transplantation of neural crest-like cells derived from induced pluripotent stem cells improves diabetic polyneuropathy in mice.
Okawa T, Kamiya H, Himeno T, Kato J, Seino Y, Fujiya A, Kondo M, Tsunekawa S, Naruse K, Hamada Y, Ozaki N, Cheng Z, Kito T, Suzuki H, Ito S, Oiso Y, Nakamura J, Isobe K. Okawa T, et al. Among authors: seino y. Cell Transplant. 2013;22(10):1767-83. doi: 10.3727/096368912X657710. Epub 2012 Oct 8. Cell Transplant. 2013. PMID: 23051637 Free article.
Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides.
Fukami A, Seino Y, Ozaki N, Yamamoto M, Sugiyama C, Sakamoto-Miura E, Himeno T, Takagishi Y, Tsunekawa S, Ali S, Drucker DJ, Murata Y, Seino Y, Oiso Y, Hayashi Y. Fukami A, et al. Among authors: seino y. Diabetes. 2013 Feb;62(2):510-8. doi: 10.2337/db12-0294. Epub 2012 Oct 25. Diabetes. 2013. PMID: 23099862 Free PMC article.
Ingestion of a moderate high-sucrose diet results in glucose intolerance with reduced liver glucokinase activity and impaired glucagon-like peptide-1 secretion.
Sakamoto E, Seino Y, Fukami A, Mizutani N, Tsunekawa S, Ishikawa K, Ogata H, Uenishi E, Kamiya H, Hamada Y, Sato H, Harada N, Toyoda Y, Miwa I, Nakamura J, Inagaki N, Oiso Y, Ozaki N. Sakamoto E, et al. Among authors: seino y. J Diabetes Investig. 2012 Oct 18;3(5):432-40. doi: 10.1111/j.2040-1124.2012.00208.x. J Diabetes Investig. 2012. PMID: 24843603 Free PMC article.
KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state.
Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y. Ogata H, et al. Among authors: seino y, seino s. J Endocrinol. 2014 Aug;222(2):191-200. doi: 10.1530/JOE-14-0161. Epub 2014 Jun 2. J Endocrinol. 2014. PMID: 24891433
Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity.
Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, Uenishi E, Seino Y, Ozaki N, Sugimura Y, Hamada Y, Kuroda A, Shinjo K, Kondo Y, Oiso Y. Ishikawa K, et al. Among authors: seino y. PLoS One. 2015 Feb 6;10(2):e0115350. doi: 10.1371/journal.pone.0115350. eCollection 2015. PLoS One. 2015. PMID: 25658116 Free PMC article.
1,475 results