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Thrombopoiesis is spatially regulated by the bone marrow vasculature.
Stegner D, vanEeuwijk JMM, Angay O, Gorelashvili MG, Semeniak D, Pinnecker J, Schmithausen P, Meyer I, Friedrich M, Dütting S, Brede C, Beilhack A, Schulze H, Nieswandt B, Heinze KG. Stegner D, et al. Among authors: semeniak d. Nat Commun. 2017 Jul 25;8(1):127. doi: 10.1038/s41467-017-00201-7. Nat Commun. 2017. PMID: 28743899 Free PMC article.
CK2β regulates thrombopoiesis and Ca2+-triggered platelet activation in arterial thrombosis.
Münzer P, Walker-Allgaier B, Geue S, Langhauser F, Geuss E, Stegner D, Aurbach K, Semeniak D, Chatterjee M, Gonzalez Menendez I, Märklin M, Quintanilla-Martinez L, Salih HR, Litchfield DW, Buchou T, Kleinschnitz C, Lang F, Nieswandt B, Pleines I, Schulze H, Gawaz M, Borst O. Münzer P, et al. Among authors: semeniak d. Blood. 2017 Dec 21;130(25):2774-2785. doi: 10.1182/blood-2017-05-784413. Epub 2017 Sep 19. Blood. 2017. PMID: 28928125 Free article.
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B.
Vögtle T, Sharma S, Mori J, Nagy Z, Semeniak D, Scandola C, Geer MJ, Smith CW, Lane J, Pollack S, Lassila R, Jouppila A, Barr AJ, Ogg DJ, Howard TD, McMiken HJ, Warwicker J, Geh C, Rowlinson R, Abbott WM, Eckly A, Schulze H, Wright GJ, Mazharian A, Fütterer K, Rajesh S, Douglas MR, Senis YA. Vögtle T, et al. Among authors: semeniak d. Elife. 2019 Aug 22;8:e46840. doi: 10.7554/eLife.46840. Elife. 2019. PMID: 31436532 Free PMC article.