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Discovery of novel 5-alkynyl-4-anilinopyrimidines as potent, orally active dual inhibitors of EGFR and Her-2 tyrosine kinases.
Bioorg Med Chem Lett. 2012 Jan 1;22(1):456-60. doi: 10.1016/j.bmcl.2011.10.103. Epub 2011 Nov 6.
Bioorg Med Chem Lett. 2012.
PMID: 22101132
Synthesis and evaluation of novel pyrimidine-based dual EGFR/Her-2 inhibitors.
Suzuki N, Shiota T, Watanabe F, Haga N, Murashi T, Ohara T, Matsuo K, Oomori N, Yari H, Dohi K, Inoue M, Iguchi M, Sentou J, Wada T.
Suzuki N, et al. Among authors: sentou j.
Bioorg Med Chem Lett. 2011 Mar 15;21(6):1601-6. doi: 10.1016/j.bmcl.2011.01.119. Epub 2011 Feb 2.
Bioorg Med Chem Lett. 2011.
PMID: 21334203
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