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Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells.
López-Valero I, Dávila D, González-Martínez J, Salvador-Tormo N, Lorente M, Saiz-Ladera C, Torres S, Gabicagogeascoa E, Hernández-Tiedra S, García-Taboada E, Mendiburu-Eliçabe M, Rodríguez-Fornés F, Sánchez-Domínguez R, Segovia JC, Sánchez-Gómez P, Matheu A, Sepúlveda JM, Velasco G. López-Valero I, et al. Among authors: sepulveda jm. Theranostics. 2020 Apr 6;10(11):5120-5136. doi: 10.7150/thno.41450. eCollection 2020. Theranostics. 2020. PMID: 32308772 Free PMC article.
Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth.
Pozo N, Zahonero C, Fernández P, Liñares JM, Ayuso A, Hagiwara M, Pérez A, Ricoy JR, Hernández-Laín A, Sepúlveda JM, Sánchez-Gómez P. Pozo N, et al. Among authors: sepulveda jm. J Clin Invest. 2013 Jun;123(6):2475-87. doi: 10.1172/JCI63623. Epub 2013 May 1. J Clin Invest. 2013. PMID: 23635774 Free PMC article.
Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide.
López-Valero I, Saiz-Ladera C, Torres S, Hernández-Tiedra S, García-Taboada E, Rodríguez-Fornés F, Barba M, Dávila D, Salvador-Tormo N, Guzmán M, Sepúlveda JM, Sánchez-Gómez P, Lorente M, Velasco G. López-Valero I, et al. Among authors: sepulveda jm. Biochem Pharmacol. 2018 Nov;157:266-274. doi: 10.1016/j.bcp.2018.09.007. Epub 2018 Sep 7. Biochem Pharmacol. 2018. PMID: 30195736 Free article.
Dacomitinib: an investigational drug for the treatment of glioblastoma.
Sepúlveda JM, Sánchez-Gómez P, Vaz Salgado MÁ, Gargini R, Balañá C. Sepúlveda JM, et al. Expert Opin Investig Drugs. 2018 Oct;27(10):823-829. doi: 10.1080/13543784.2018.1528225. Epub 2018 Oct 5. Expert Opin Investig Drugs. 2018. PMID: 30247945 Review.
A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.
Zhu L, Retana D, García-Gómez P, Álvaro-Espinosa L, Priego N, Masmudi-Martín M, Yebra N, Miarka L, Hernández-Encinas E, Blanco-Aparicio C, Martínez S, Sobrino C, Ajenjo N, Artiga MJ, Ortega-Paino E, Torres-Ruiz R, Rodríguez-Perales S; RENACER; Soffietti R, Bertero L, Cassoni P, Weiss T, Muñoz J, Sepúlveda JM, González-León P, Jiménez-Roldán L, Moreno LM, Esteban O, Pérez-Núñez Á, Hernández-Laín A, Toldos O, Ruano Y, Alcázar L, Blasco G, Fernández-Alén J, Caleiras E, Lafarga M, Megías D, Graña-Castro O, Nör C, Taylor MD, Young LS, Varešlija D, Cosgrove N, Couch FJ, Cussó L, Desco M, Mouron S, Quintela-Fandino M, Weller M, Pastor J, Valiente M. Zhu L, et al. Among authors: sepulveda jm. EMBO Mol Med. 2022 Mar 7;14(3):e14552. doi: 10.15252/emmm.202114552. Epub 2022 Feb 17. EMBO Mol Med. 2022. PMID: 35174975 Free PMC article.
The role of pharmacogenomics in metastatic renal cell carcinoma.
Castellano D, Virizuela JA, Cruz J, Sepulveda JM, Sáez MI, Paz-Ares L. Castellano D, et al. Among authors: sepulveda jm. Cancer Metastasis Rev. 2012 Sep;31 Suppl 1:S29-32. doi: 10.1007/s10555-012-9356-x. Cancer Metastasis Rev. 2012. PMID: 22723081 Review.
97 results