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Inability of ovarian cancers to upregulate their MHC-class I surface expression marks their aggressiveness and increased susceptibility to NK cell-mediated cytotoxicity.
Chovatiya N, Kaur K, Huerta-Yepez S, Chen PC, Neal A, DiBernardo G, Gumrukcu S, Memarzadeh S, Jewett A. Chovatiya N, et al. Among authors: gumrukcu s. Cancer Immunol Immunother. 2022 Dec;71(12):2929-2941. doi: 10.1007/s00262-022-03192-7. Epub 2022 May 4. Cancer Immunol Immunother. 2022. PMID: 35507102 Free PMC article.