Insufficient evidence for a role of SERPINF1 in otosclerosis.
Valgaeren H, Sommen M, Beyens M, Vandeweyer G, Schrauwen I, Schepers A, Schatteman I, Topsakal V, Dhooge I, Kunst H, Zanetti D, Huber AM, Hoischen A, Fransen E, Van Camp G.
Valgaeren H, et al.
Mol Genet Genomics. 2019 Aug;294(4):1001-1006. doi: 10.1007/s00438-019-01558-8. Epub 2019 Apr 9.
Mol Genet Genomics. 2019.
PMID: 30968248
The genetic causes of otosclerosis remain largely unidentified. Only mutations in a single gene, SERPINF1, were previously published in patients with familial otosclerosis. ...We could also not find evidence for a pathogenic role in otosclerosis for 5' UTR variants in the …
The genetic causes of otosclerosis remain largely unidentified. Only mutations in a single gene, SERPINF1, were previously published …