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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 1
1994 7
1995 8
1996 5
1997 6
1998 19
1999 12
2000 14
2001 17
2002 16
2003 21
2004 16
2005 10
2006 12
2007 10
2008 11
2009 13
2010 12
2011 15
2012 14
2013 15
2014 24
2015 23
2016 18
2017 19
2018 25
2019 26
2020 38
2021 26
2022 29
2023 30
2024 19

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473 results

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Page 1
SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/beta-catenin signaling pathway.
Tian S, Peng P, Li J, Deng H, Zhan N, Zeng Z, Dong W. Tian S, et al. Aging (Albany NY). 2020 Feb 24;12(4):3574-3593. doi: 10.18632/aging.102831. Epub 2020 Feb 24. Aging (Albany NY). 2020. PMID: 32091407 Free PMC article.
In this study, we investigated the role of SERPINH1 in gastric cancer (GC) progression. GC patient tissues show significantly higher SERPINH1 mRNA and protein levels than normal gastric mucosal tissues. ...In SERPINH1-silenced SGC-7901 cells, survival, colony …
In this study, we investigated the role of SERPINH1 in gastric cancer (GC) progression. GC patient tissues show significantly higher …
Circular RNA circ-TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA.
Pan X, Huang B, Ma Q, Ren J, Liu Y, Wang C, Zhang D, Fu J, Ran L, Yu T, Li H, Wang X, Yang F, Liang C, Zhang Y, Wang S, Ren J, Li W, Wang Y, Xiao B. Pan X, et al. Clin Transl Med. 2022 Jul;12(7):e994. doi: 10.1002/ctm2.994. Clin Transl Med. 2022. PMID: 35876041 Free PMC article.
Mechanistically, we elucidated that circ-TNPO3 directly bound to IGF2BP2 protein and then destabilized SERPINH1 mRNA. Moreover, IGF2BP2/SERPINH1 axis was responsible for circ-TNPO3's function of inhibiting ccRCC metastasis. ...CONCLUSIONS: Circ-TNPO3 can suppress cc …
Mechanistically, we elucidated that circ-TNPO3 directly bound to IGF2BP2 protein and then destabilized SERPINH1 mRNA. Moreover, IGF2B …
High SERPINH1 expression predicts poor prognosis in lung adenocarcinoma.
Zhang H, Yan X, Gu H, Xue Q, Liu X. Zhang H, et al. J Thorac Dis. 2022 Dec;14(12):4785-4802. doi: 10.21037/jtd-22-1518. J Thorac Dis. 2022. PMID: 36647484 Free PMC article.
The analysis of SERPINH1 and the TMB revealed a superior survival advantage for patients with high TMB and high SERPINH1 expression, and worse survival for those with low TMB and high SERPINH1 expression. ...The analysis of the immune checkpoints and anti-tum …
The analysis of SERPINH1 and the TMB revealed a superior survival advantage for patients with high TMB and high SERPINH1 expre …
SERPINH1 is a Potential Prognostic Biomarker and Correlated With Immune Infiltration: A Pan-Cancer Analysis.
Wang Y, Gu W, Wen W, Zhang X. Wang Y, et al. Front Genet. 2022 Jan 4;12:756094. doi: 10.3389/fgene.2021.756094. eCollection 2021. Front Genet. 2022. PMID: 35058967 Free PMC article.
However, the role of SERPINH1 in pan-cancer is largely unexplored. Methods: SERPINH1 expression and the correlation with prognosis in human pan-cancer were analyzed by the Cancer Genome Atlas and the Genotype-Tissue Expression dataset. ...Results: SERPINH1 wa …
However, the role of SERPINH1 in pan-cancer is largely unexplored. Methods: SERPINH1 expression and the correlation with progn …
Prognostic and immunological role of SERPINH1 in pan-cancer.
Zhong H, Wang Z, Wei X, Liu Y, Huang X, Mo X, Tang W. Zhong H, et al. Front Genet. 2022 Aug 29;13:900495. doi: 10.3389/fgene.2022.900495. eCollection 2022. Front Genet. 2022. PMID: 36105106 Free PMC article.
The genomic alterations of SERPINH1 were studied using the c-BioPortal database. The influence of SERPINH1 on prognosis was analyzed using Kaplan-Meier plotter. ...High expression of SERPINH1 may contribute to tumor immune-suppressive status. Also, SERPINH …
The genomic alterations of SERPINH1 were studied using the c-BioPortal database. The influence of SERPINH1 on prognosis was an …
Splicing factor derived circular RNA circCAMSAP1 accelerates nasopharyngeal carcinoma tumorigenesis via a SERPINH1/c-Myc positive feedback loop.
Wang Y, Yan Q, Mo Y, Liu Y, Wang Y, Zhang S, Guo C, Wang F, Li G, Zeng Z, Xiong W. Wang Y, et al. Mol Cancer. 2022 Feb 28;21(1):62. doi: 10.1186/s12943-022-01502-2. Mol Cancer. 2022. PMID: 35227262 Free PMC article.
RESULTS: We found that circCAMSAP1 was highly expressed in NPC tissues and promoted NPC proliferation and metastasis. Additionally, circCAMSAP1 promoted SERPINH1 expression through improved SERPINH1 mRNA stability by binding to the 3'-untranslated region (3'UTR) of …
RESULTS: We found that circCAMSAP1 was highly expressed in NPC tissues and promoted NPC proliferation and metastasis. Additionally, circCAMS …
SERPINH1, Targeted by miR-29b, Modulated Proliferation and Migration of Human Retinal Endothelial Cells Under High Glucose Conditions.
Hu L, Liu Y, Wei C, Jin H, Mei L, Wu C. Hu L, et al. Diabetes Metab Syndr Obes. 2021 Aug 4;14:3471-3483. doi: 10.2147/DMSO.S307771. eCollection 2021. Diabetes Metab Syndr Obes. 2021. PMID: 34377003 Free PMC article.
SERPINH1 was a target of miR-29b and was suppressed by miR-29 in HRECs. SERPINH1 overexpression promoted HREC proliferation and migration. ...
SERPINH1 was a target of miR-29b and was suppressed by miR-29 in HRECs. SERPINH1 overexpression promoted HREC proliferation an …
SERPINH1 enhances the malignancy of osteosarcoma via PI3K-Akt signaling pathway.
Xia K, Huang X, Zhao Y, Yang I, Guo W. Xia K, et al. Transl Oncol. 2024 Jan;39:101802. doi: 10.1016/j.tranon.2023.101802. Epub 2023 Oct 13. Transl Oncol. 2024. PMID: 37839175 Free PMC article.
METHODS: First, we examined the expression of SERPINH1 in osteosarcoma and analyzed publicly available datasets to investigate whether SERPINH1 expression was associated with the prognosis of osteosarcoma. ...In addition, we constructed a subcutaneous xenograft tumo …
METHODS: First, we examined the expression of SERPINH1 in osteosarcoma and analyzed publicly available datasets to investigate whethe …
By using machine learning and in vitro testing, SERPINH1 functions as a novel tumorigenic and immunogenic gene and predicts immunotherapy response in osteosarcoma.
Xia G, Wu S, Luo K, Cui X. Xia G, et al. Front Oncol. 2023 Apr 5;13:1180191. doi: 10.3389/fonc.2023.1180191. eCollection 2023. Front Oncol. 2023. PMID: 37091161 Free PMC article.
It is also more expressed in tumor samples than in healthy samples. SERPINH1 might forecast the effects of immunotherapy. Additionally, immune cells are interacted with through checkpoint, cytokine, and growth factor pathways in osteosarcomas with high SERPINH1 leve …
It is also more expressed in tumor samples than in healthy samples. SERPINH1 might forecast the effects of immunotherapy. Additionall …
Proteomics reveals plasma protein SERPINH1 as a potential diagnostic biomarkers for myxomatous mitral valve disease stage B2.
Zhou Q, Wu Z, Li L, Zhou H, Chen Y, Guo S, Guo Y, Ma X, Zhang J, Feng W, Cui X, Qiu C, Xu M, Deng G. Zhou Q, et al. J Proteomics. 2023 Jun 30;282:104924. doi: 10.1016/j.jprot.2023.104924. Epub 2023 May 3. J Proteomics. 2023. PMID: 37146676
CONCLUSION: Plasma SERPINH1 has good predictive and diagnostic value at dog with MMVD stage B2, suggesting that SERPINH1 may be used as a biomarker for early prediction and diagnosis of stage B2 of MMVD. ...It is also the first study to consider SERPINH1 as a …
CONCLUSION: Plasma SERPINH1 has good predictive and diagnostic value at dog with MMVD stage B2, suggesting that SERPINH1 may b …
473 results