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Receptors for protons or lipid messengers or both?
Seuwen K, Ludwig MG, Wolf RM. Seuwen K, et al. J Recept Signal Transduct Res. 2006;26(5-6):599-610. doi: 10.1080/10799890600932220. J Recept Signal Transduct Res. 2006. PMID: 17118800 Review.
Proton-sensing G-protein-coupled receptors.
Ludwig MG, Vanek M, Guerini D, Gasser JA, Jones CE, Junker U, Hofstetter H, Wolf RM, Seuwen K. Ludwig MG, et al. Among authors: seuwen k. Nature. 2003 Sep 4;425(6953):93-8. doi: 10.1038/nature01905. Nature. 2003. PMID: 12955148
Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization.
Surdziel E, Clay I, Nigsch F, Thiemeyer A, Allard C, Hoffman G, Reece-Hoyes JS, Phadke T, Gambert R, Keller CG, Ludwig MG, Baumgarten B, Frederiksen M, Schübeler D, Seuwen K, Bouwmeester T, Fodor BD. Surdziel E, et al. Among authors: seuwen k. PLoS One. 2017 Aug 24;12(8):e0183679. doi: 10.1371/journal.pone.0183679. eCollection 2017. PLoS One. 2017. PMID: 28837623 Free PMC article.
CNS distribution, signalling properties and central effects of G-protein coupled receptor 4.
Hosford PS, Mosienko V, Kishi K, Jurisic G, Seuwen K, Kinzel B, Ludwig MG, Wells JA, Christie IN, Koolen L, Abdala AP, Liu BH, Gourine AV, Teschemacher AG, Kasparov S. Hosford PS, et al. Among authors: seuwen k. Neuropharmacology. 2018 Aug;138:381-392. doi: 10.1016/j.neuropharm.2018.06.007. Epub 2018 Jun 9. Neuropharmacology. 2018. PMID: 29894771 Free PMC article.
G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation.
de Vallière C, Wang Y, Eloranta JJ, Vidal S, Clay I, Spalinger MR, Tcymbarevich I, Terhalle A, Ludwig MG, Suply T, Fried M, Kullak-Ublick GA, Frey-Wagner I, Scharl M, Seuwen K, Wagner CA, Rogler G. de Vallière C, et al. Among authors: seuwen k. Inflamm Bowel Dis. 2015 Jun;21(6):1269-81. doi: 10.1097/MIB.0000000000000375. Inflamm Bowel Dis. 2015. PMID: 25856770 Free PMC article.
PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons.
Kumar NN, Velic A, Soliz J, Shi Y, Li K, Wang S, Weaver JL, Sen J, Abbott SB, Lazarenko RM, Ludwig MG, Perez-Reyes E, Mohebbi N, Bettoni C, Gassmann M, Suply T, Seuwen K, Guyenet PG, Wagner CA, Bayliss DA. Kumar NN, et al. Among authors: seuwen k. Science. 2015 Jun 12;348(6240):1255-60. doi: 10.1126/science.aaa0922. Epub 2015 Jun 11. Science. 2015. PMID: 26068853 Free PMC article.
The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment.
de Vallière C, Vidal S, Clay I, Jurisic G, Tcymbarevich I, Lang S, Ludwig MG, Okoniewski M, Eloranta JJ, Kullak-Ublick GA, Wagner CA, Rogler G, Seuwen K. de Vallière C, et al. Among authors: seuwen k. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G475-90. doi: 10.1152/ajpgi.00408.2014. Epub 2015 Jul 23. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 26206859 Free article.
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