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The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels.
J Pharmacol Exp Ther. 2001 Jul;298(1):15-24.
J Pharmacol Exp Ther. 2001.
PMID: 11408520
Constitutive expression of functional GABA(B) receptors in mIL-tsA58 cells requires both GABA(B(1)) and GABA(B(2)) genes.
Chronwall BM, Davis TD, Severidt MW, Wolfe SE, McCarson KE, Beatty DM, Low MJ, Morris SJ, Enna SJ.
Chronwall BM, et al. Among authors: severidt mw.
J Neurochem. 2001 Jun;77(5):1237-47. doi: 10.1046/j.1471-4159.2001.00323.x.
J Neurochem. 2001.
PMID: 11389174
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