Sewitz S - Search Results

1

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.

Javierre BM, Burren OS, Wilder SP, Kreuzhuber R, Hill SM, Sewitz S, Cairns J, Wingett SW, Várnai C, Thiecke MJ, Burden F, Farrow S, Cutler AJ, Rehnström K, Downes K, Grassi L, Kostadima M, Freire-Pritchett P, Wang F; BLUEPRINT Consortium; Stunnenberg HG, Todd JA, Zerbino DR, Stegle O, Ouwehand WH, Frontini M, Wallace C, Spivakov M, Fraser P. Javierre BM, et al. Among authors: sewitz s. Cell. 2016 Nov 17;167(5):1369-1384.e19. doi: 10.1016/j.cell.2016.09.037. Cell. 2016. PMID: 27863249 Free PMC article.

2

Higher order assembly: folding the chromosome.

Sewitz SA, Fahmi Z, Lipkow K. Sewitz SA, et al. Curr Opin Struct Biol. 2017 Feb;42:162-168. doi: 10.1016/j.sbi.2017.02.004. Epub 2017 Mar 8. Curr Opin Struct Biol. 2017. PMID: 28284913 Free article. Review.

3

Systems Biology Approaches for Understanding Genome Architecture.

Sewitz S, Lipkow K. Sewitz S, et al. Methods Mol Biol. 2016;1431:109-26. doi: 10.1007/978-1-4939-3631-1_9. Methods Mol Biol. 2016. PMID: 27283305

4

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression.

Fernando H, Sewitz S, Darot J, Tavaré S, Huppert JL, Balasubramanian S. Fernando H, et al. Among authors: sewitz s. Nucleic Acids Res. 2009 Nov;37(20):6716-22. doi: 10.1093/nar/gkp740. Epub 2009 Sep 10. Nucleic Acids Res. 2009. PMID: 19745055 Free PMC article.

5

A complex network framework for unbiased statistical analyses of DNA-DNA contact maps.

Kruse K, Sewitz S, Babu MM. Kruse K, et al. Among authors: sewitz s. Nucleic Acids Res. 2013 Jan;41(2):701-10. doi: 10.1093/nar/gks1096. Epub 2012 Nov 21. Nucleic Acids Res. 2013. PMID: 23175602 Free PMC article.

6

Complete nucleotide sequence of Tn10.

Chalmers R, Sewitz S, Lipkow K, Crellin P. Chalmers R, et al. Among authors: sewitz s. J Bacteriol. 2000 May;182(10):2970-2. doi: 10.1128/JB.182.10.2970-2972.2000. J Bacteriol. 2000. PMID: 10781570 Free PMC article.

7

A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression.

Waller ZA, Sewitz SA, Hsu ST, Balasubramanian S. Waller ZA, et al. Among authors: sewitz sa. J Am Chem Soc. 2009 Sep 9;131(35):12628-33. doi: 10.1021/ja901892u. J Am Chem Soc. 2009. PMID: 19689109 Free PMC article.

8

Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression.

Bejugam M, Sewitz S, Shirude PS, Rodriguez R, Shahid R, Balasubramanian S. Bejugam M, et al. Among authors: sewitz s. J Am Chem Soc. 2007 Oct 31;129(43):12926-7. doi: 10.1021/ja075881p. Epub 2007 Oct 5. J Am Chem Soc. 2007. PMID: 17918848 Free PMC article. No abstract available.

9

Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.

Bejugam M, Gunaratnam M, Müller S, Sanders DA, Sewitz S, Fletcher JA, Neidle S, Balasubramanian S. Bejugam M, et al. Among authors: sewitz s. ACS Med Chem Lett. 2010 Jul 1;1(7):306-10. doi: 10.1021/ml100062z. eCollection 2010 Oct 14. ACS Med Chem Lett. 2010. PMID: 24900212 Free PMC article.

10

An integrated model of transcription factor diffusion shows the importance of intersegmental transfer and quaternary protein structure for target site finding.

Schmidt HG, Sewitz S, Andrews SS, Lipkow K. Schmidt HG, et al. Among authors: sewitz s. PLoS One. 2014 Oct 21;9(10):e108575. doi: 10.1371/journal.pone.0108575. eCollection 2014. PLoS One. 2014. PMID: 25333780 Free PMC article.

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