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Gene regulation through nuclear organization.
Sexton T, Schober H, Fraser P, Gasser SM. Sexton T, et al. Nat Struct Mol Biol. 2007 Nov;14(11):1049-55. doi: 10.1038/nsmb1324. Epub 2007 Nov 5. Nat Struct Mol Biol. 2007. PMID: 17984967
Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus.
Taylor T, Sikorska N, Shchuka VM, Chahar S, Ji C, Macpherson NN, Moorthy SD, de Kort MAC, Mullany S, Khader N, Gillespie ZE, Langroudi L, Tobias IC, Lenstra TL, Mitchell JA, Sexton T. Taylor T, et al. Among authors: sexton t. Genes Dev. 2022 Jun 1;36(11-12):699-717. doi: 10.1101/gad.349489.122. Epub 2022 Jun 16. Genes Dev. 2022. PMID: 35710138 Free PMC article.
Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions.
Cattoni DI, Cardozo Gizzi AM, Georgieva M, Di Stefano M, Valeri A, Chamousset D, Houbron C, Déjardin S, Fiche JB, González I, Chang JM, Sexton T, Marti-Renom MA, Bantignies F, Cavalli G, Nollmann M. Cattoni DI, et al. Among authors: sexton t. Nat Commun. 2017 Nov 24;8(1):1753. doi: 10.1038/s41467-017-01962-x. Nat Commun. 2017. PMID: 29170434 Free PMC article.
243 results