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A framework for validating AI in precision medicine: considerations from the European ITFoC consortium.
Tsopra R, Fernandez X, Luchinat C, Alberghina L, Lehrach H, Vanoni M, Dreher F, Sezerman OU, Cuggia M, de Tayrac M, Miklasevics E, Itu LM, Geanta M, Ogilvie L, Godey F, Boldisor CN, Campillo-Gimenez B, Cioroboiu C, Ciusdel CF, Coman S, Hijano Cubelos O, Itu A, Lange B, Le Gallo M, Lespagnol A, Mauri G, Soykam HO, Rance B, Turano P, Tenori L, Vignoli A, Wierling C, Benhabiles N, Burgun A. Tsopra R, et al. Among authors: sezerman ou. BMC Med Inform Decis Mak. 2021 Oct 2;21(1):274. doi: 10.1186/s12911-021-01634-3. BMC Med Inform Decis Mak. 2021. PMID: 34600518 Free PMC article.
A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer.
Wagner AH, Walsh B, Mayfield G, Tamborero D, Sonkin D, Krysiak K, Deu-Pons J, Duren RP, Gao J, McMurry J, Patterson S, Del Vecchio Fitz C, Pitel BA, Sezerman OU, Ellrott K, Warner JL, Rieke DT, Aittokallio T, Cerami E, Ritter DI, Schriml LM, Freimuth RR, Haendel M, Raca G, Madhavan S, Baudis M, Beckmann JS, Dienstmann R, Chakravarty D, Li XS, Mockus S, Elemento O, Schultz N, Lopez-Bigas N, Lawler M, Goecks J, Griffith M, Griffith OL, Margolin AA; Variant Interpretation for Cancer Consortium. Wagner AH, et al. Among authors: sezerman ou. Nat Genet. 2020 Apr;52(4):448-457. doi: 10.1038/s41588-020-0603-8. Epub 2020 Apr 3. Nat Genet. 2020. PMID: 32246132 Free PMC article.
Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion.
Wang X, Istvanffy R, Ye L, Teller S, Laschinger M, Diakopoulos KN, Görgülü K, Li Q, Ren L, Jäger C, Steiger K, Muckenhuber A, Vilne B, Çifcibaşı K, Reyes CM, Yurteri Ü, Kießler M, Gürçınar IH, Sugden M, Yıldızhan SE, Sezerman OU, Çilingir S, Süyen G, Reichert M, Schmid RM, Bärthel S, Oellinger R, Krüger A, Rad R, Saur D, Algül H, Friess H, Lesina M, Ceyhan GO, Demir IE. Wang X, et al. Among authors: sezerman ou. J Clin Invest. 2023 Nov 1;133(21):e166333. doi: 10.1172/JCI166333. J Clin Invest. 2023. PMID: 37607005 Free PMC article.
Metabolomic Analyses to Identify Candidate Biomarkers of Cystinosis.
Nemutlu E, Ozaltin F, Yabanoglu-Ciftci S, Gulhan B, Eylem CC, Baysal İ, Gök-Topak ED, Ulubayram K, Sezerman OU, Ucar G, Kır S, Topaloglu R. Nemutlu E, et al. Among authors: sezerman ou. Int J Mol Sci. 2023 Jan 30;24(3):2603. doi: 10.3390/ijms24032603. Int J Mol Sci. 2023. PMID: 36768921 Free PMC article.
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