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Did you mean sftpc (538 results)?
Retinal degeneration mutation in Sftpa1tm1Kor/J and Sftpd -/- targeted mice.
Bhatti F, Kung JW, Vieira F. Bhatti F, et al. PLoS One. 2018 Jul 3;13(7):e0199824. doi: 10.1371/journal.pone.0199824. eCollection 2018. PLoS One. 2018. PMID: 29969487 Free PMC article.
We hypothesized that gene deletion of Sftpa1 and Sftpd (Sftpa1tm1Kor/J and Sftpd-/-) results in early retinal degeneration in these mice. ...We can therefore conclude that loss of Sftpa1 and Sftpd do not result in retinal degeneration. We have now generated r …
We hypothesized that gene deletion of Sftpa1 and Sftpd (Sftpa1tm1Kor/J and Sftpd-/-) results in early retinal degeneration in …
Identification of hub genes and pathways in lung metastatic colorectal cancer.
Dai W, Guo C, Wang Y, Li Y, Xie R, Wu J, Yao B, Xie D, He L, Li Y, Huang H, Wang Y, Liu S. Dai W, et al. BMC Cancer. 2023 Apr 6;23(1):323. doi: 10.1186/s12885-023-10792-8. BMC Cancer. 2023. PMID: 37024866 Free PMC article.
RESULTS: The DEGs were enriched in surfactant metabolism, cell-cell communication and chemokine signaling pathways. The defined hub genes were included CLU, SFTPD, CCL18, SPP1, APOE, BGN and MMP3. Among them, CLU, SFTPD and CCL18 might be associated with the specifi …
RESULTS: The DEGs were enriched in surfactant metabolism, cell-cell communication and chemokine signaling pathways. The defined hub genes we …
Genetic Variants of DMBT1 and SFTPD and Disease Severity in Paediatric Inflammatory Bowel Disease-A Polish Population-Based Study.
Glapa-Nowak A, Szczepanik M, Banaszkiewicz A, Iwańczak B, Kwiecień J, Szaflarska-Popławska A, Grzybowska-Chlebowczyk U, Osiecki M, Kierkuś J, Banasiuk M, Banasiewicz T, Madsen J, Walkowiak J. Glapa-Nowak A, et al. Children (Basel). 2021 Oct 21;8(11):946. doi: 10.3390/children8110946. Children (Basel). 2021. PMID: 34828659 Free PMC article.
Deleted in malignant brain tumours 1 protein (DMBT1) and surfactant protein D (SFTPD) are antimicrobial peptides previously linked to inflammatory bowel disease (IBD) susceptibility. ...TT; p = 0.048). In conclusion, selected polymorphisms of DMBT1 and SFTPD might b …
Deleted in malignant brain tumours 1 protein (DMBT1) and surfactant protein D (SFTPD) are antimicrobial peptides previously linked to …
Association of serum surfactant protein D and SFTPD gene variants with asthma in Danish children, adolescents, and young adults.
Hoffmann-Petersen B, Suffolk R, Petersen JJH, Petersen TH, Brasch-Andersen C, Høst A, Halken S, Sorensen GL, Agertoft L. Hoffmann-Petersen B, et al. Immun Inflamm Dis. 2022 Feb;10(2):189-200. doi: 10.1002/iid3.560. Epub 2021 Nov 15. Immun Inflamm Dis. 2022. PMID: 34780682 Free PMC article.
RESULTS: No differences were found in mean levels of sSP-D and SFTPD genotype among subjects with current asthma, no current asthma, and controls. Serum SP-D and SFTPD genotype were not associated with any clinical parameters of asthma. ...
RESULTS: No differences were found in mean levels of sSP-D and SFTPD genotype among subjects with current asthma, no current asthma, …
Effects of ALOX5, IL6R and SFTPD gene polymorphisms on the risk of lung cancer: A case-control study in China.
Wei X, Wang C, Feng H, Li B, Jiang P, Yang J, Zhu D, Zhang S, Jin T, Meng Y. Wei X, et al. Int Immunopharmacol. 2020 Feb;79:106155. doi: 10.1016/j.intimp.2019.106155. Epub 2020 Jan 7. Int Immunopharmacol. 2020. PMID: 31918059
BACKGROUND: ALOX5, IL6R and SFTPD are all immune related genes that may be involved in the development of lung cancer. ...However, rs892690, rs745986 and rs2115819 of ALOX5 were associated with an increased risk of disease in nonsmokers, while rs2245121 of SFTPD was …
BACKGROUND: ALOX5, IL6R and SFTPD are all immune related genes that may be involved in the development of lung cancer. ...However, rs …
Association between the surfactant protein D (SFTPD) gene and subclinical carotid artery atherosclerosis.
Sorensen GL, Bladbjerg EM, Steffensen R, Tan Q, Madsen J, Drivsholm T, Holmskov U. Sorensen GL, et al. Atherosclerosis. 2016 Mar;246:7-12. doi: 10.1016/j.atherosclerosis.2015.12.037. Epub 2015 Dec 29. Atherosclerosis. 2016. PMID: 26748346
Associations between cardiovascular traits and the levels of pSP-D (n = 687) or two coding SFTPD SNPs rs3088308 and rs721917 (n = 396) were investigated using multiple linear regressions and logistic regressions. RESULTS: There was no significant association between pSP-D …
Associations between cardiovascular traits and the levels of pSP-D (n = 687) or two coding SFTPD SNPs rs3088308 and rs721917 (n = 396 …
Identification of Crucial Genes and Signaling Pathways in Alectinib-Resistant Lung Adenocarcinoma Using Bioinformatic Analysis.
Li Z, Fan Y, Ma Y, Meng N, Li D, Wang D, Lian J, Hu C. Li Z, et al. Mol Biotechnol. 2023 Dec 24. doi: 10.1007/s12033-023-00973-y. Online ahead of print. Mol Biotechnol. 2023. PMID: 38142454
The networks of kinase, miRNA, and transcription-factor targets of SFTPD were explored using LinkedOmics. The drug sensitivity analysis of SFTPD was analyzed using the RNAactDrug database. ...The SFTPD expression was negatively correlated with the drug sensit …
The networks of kinase, miRNA, and transcription-factor targets of SFTPD were explored using LinkedOmics. The drug sensitivity analys …
Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D.
Kingma PS, Zhang L, Ikegami M, Hartshorn K, McCormack FX, Whitsett JA. Kingma PS, et al. J Biol Chem. 2006 Aug 25;281(34):24496-505. doi: 10.1074/jbc.M600651200. Epub 2006 Jun 20. J Biol Chem. 2006. PMID: 16787926 Free article.
In this study, the function of the collagenous domain was evaluated by expressing a SP-D collagen deletion mutant protein (rSftpdCDM) in wild type and SP-D null mice (Sftpd(-/-)). rSftpdCDM formed disulfide-linked trimers that further oligomerized into higher order structu …
In this study, the function of the collagenous domain was evaluated by expressing a SP-D collagen deletion mutant protein (rSftpdCDM) in wil …
Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells.
Davé V, Childs T, Whitsett JA. Davé V, et al. J Biol Chem. 2004 Aug 13;279(33):34578-88. doi: 10.1074/jbc.M404296200. Epub 2004 Jun 1. J Biol Chem. 2004. PMID: 15173172 Free article.
Here, we identify a role of nuclear factor of activated T cells (NFATs) in regulation of murine SP-D gene (Sftpd) transcription. An NFAT-dependent enhancer modulated by NFATs or calcineurin and sensitive to cyclosporin was identified in the Sftpd promoter. ...NFATc3 …
Here, we identify a role of nuclear factor of activated T cells (NFATs) in regulation of murine SP-D gene (Sftpd) transcription. An N …
139 results