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Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis.
J Neurosci. 2010 Aug 4;30(31):10541-50. doi: 10.1523/JNEUROSCI.0146-10.2010.
J Neurosci. 2010.
PMID: 20685997
Free PMC article.
Identifying polyglutamine protein species in situ that best predict neurodegeneration.
Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, Osmand A, Gray M, Thulasiramin V, Saudou F, Segal M, Yang XW, Masliah E, Thompson LM, Muchowski PJ, Weisgraber KH, Finkbeiner S.
Miller J, et al. Among authors: shaby ba.
Nat Chem Biol. 2011 Oct 30;7(12):925-34. doi: 10.1038/nchembio.694.
Nat Chem Biol. 2011.
PMID: 22037470
Free PMC article.
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Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration.
Tsvetkov AS, Arrasate M, Barmada S, Ando DM, Sharma P, Shaby BA, Finkbeiner S.
Tsvetkov AS, et al. Among authors: shaby ba.
Nat Chem Biol. 2013 Sep;9(9):586-92. doi: 10.1038/nchembio.1308. Epub 2013 Jul 21.
Nat Chem Biol. 2013.
PMID: 23873212
Free PMC article.
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Nrf2 mitigates LRRK2- and α-synuclein-induced neurodegeneration by modulating proteostasis.
Skibinski G, Hwang V, Ando DM, Daub A, Lee AK, Ravisankar A, Modan S, Finucane MM, Shaby BA, Finkbeiner S.
Skibinski G, et al. Among authors: shaby ba.
Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1165-1170. doi: 10.1073/pnas.1522872114. Epub 2016 Dec 27.
Proc Natl Acad Sci U S A. 2017.
PMID: 28028237
Free PMC article.
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A three-groups model for high-throughput survival screens.
Shaby BA, Skibinski G, Ando M, LaDow ES, Finkbeiner S.
Shaby BA, et al.
Biometrics. 2016 Sep;72(3):936-44. doi: 10.1111/biom.12479. Epub 2016 Jan 28.
Biometrics. 2016.
PMID: 26821783
Free PMC article.
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Machine learning for modeling animal movement.
Wijeyakulasuriya DA, Eisenhauer EW, Shaby BA, Hanks EM.
Wijeyakulasuriya DA, et al. Among authors: shaby ba.
PLoS One. 2020 Jul 27;15(7):e0235750. doi: 10.1371/journal.pone.0235750. eCollection 2020.
PLoS One. 2020.
PMID: 32716917
Free PMC article.
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Extreme value analysis for evaluating ozone control strategies.
Reich B, Cooley D, Foley K, Napelenok S, Shaby B.
Reich B, et al.
Ann Appl Stat. 2013 Jun 1;7(2):739-762. doi: 10.1214/13-AOAS628.
Ann Appl Stat. 2013.
PMID: 24587842
Free PMC article.
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A HIERARCHICAL MAX-STABLE SPATIAL MODEL FOR EXTREME PRECIPITATION.
Reich BJ, Shaby BA.
Reich BJ, et al. Among authors: shaby ba.
Ann Appl Stat. 2012;6(4):1430-1451. doi: 10.1214/12-AOAS591.
Ann Appl Stat. 2012.
PMID: 23795226
Free PMC article.
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