Shain KH - Search Results

1

Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma.

Meads MB, Fang B, Mathews L, Gemmer J, Nong L, Rosado-Lopez I, Nguyen T, Ring JE, Matsui W, MacLeod AR, Pachter JA, Hazlehurst LA, Koomen JM, Shain KH. Meads MB, et al. Among authors: shain kh. Oncogene. 2016 May;35(21):2723-34. doi: 10.1038/onc.2015.334. Epub 2015 Sep 21. Oncogene. 2016. PMID: 26387544 Free PMC article.

2

The tumor microenvironment as a determinant of cancer cell survival: a possible mechanism for de novo drug resistance.

Shain KH, Landowski TH, Dalton WS. Shain KH, et al. Curr Opin Oncol. 2000 Nov;12(6):557-63. doi: 10.1097/00001622-200011000-00008. Curr Opin Oncol. 2000. PMID: 11085455 Review.

3

Multiple Myeloma: New Insights and Therapeutic Approaches.

Anderson KC, Kyle RA, Dalton WS, Landowski T, Shain K, Jove R, Hazlehurst L, Berenson J. Anderson KC, et al. Hematology Am Soc Hematol Educ Program. 2000:147-165. doi: 10.1182/asheducation-2000.1.147. Hematology Am Soc Hematol Educ Program. 2000. PMID: 11701540

4

Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model.

Hazlehurst LA, Enkemann SA, Beam CA, Argilagos RF, Painter J, Shain KH, Saporta S, Boulware D, Moscinski L, Alsina M, Dalton WS. Hazlehurst LA, et al. Among authors: shain kh. Cancer Res. 2003 Nov 15;63(22):7900-6. Cancer Res. 2003. PMID: 14633719

5

Targeting the bone marrow microenvironment in hematologic malignancies.

Dalton WS, Hazlehurst L, Shain K, Landowski T, Alsina M. Dalton WS, et al. Semin Hematol. 2004 Apr;41(2 Suppl 4):1-5. doi: 10.1053/j.seminhematol.2004.02.001. Semin Hematol. 2004. PMID: 15190509 Review.

6

Bone marrow stroma confers resistance to Apo2 ligand/TRAIL in multiple myeloma in part by regulating c-FLIP.

Perez LE, Parquet N, Shain K, Nimmanapalli R, Alsina M, Anasetti C, Dalton W. Perez LE, et al. J Immunol. 2008 Feb 1;180(3):1545-55. doi: 10.4049/jimmunol.180.3.1545. J Immunol. 2008. PMID: 18209050

7

Beta1 integrin adhesion enhances IL-6-mediated STAT3 signaling in myeloma cells: implications for microenvironment influence on tumor survival and proliferation.

Shain KH, Yarde DN, Meads MB, Huang M, Jove R, Hazlehurst LA, Dalton WS. Shain KH, et al. Cancer Res. 2009 Feb 1;69(3):1009-15. doi: 10.1158/0008-5472.CAN-08-2419. Epub 2009 Jan 20. Cancer Res. 2009. PMID: 19155309 Free PMC article.

8

Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma.

Yarde DN, Oliveira V, Mathews L, Wang X, Villagra A, Boulware D, Shain KH, Hazlehurst LA, Alsina M, Chen DT, Beg AA, Dalton WS. Yarde DN, et al. Among authors: shain kh. Cancer Res. 2009 Dec 15;69(24):9367-75. doi: 10.1158/0008-5472.CAN-09-2616. Cancer Res. 2009. PMID: 19934314 Free PMC article.

9

Environmental-mediated drug resistance: a target for multiple myeloma therapy.

Shain KH, Dalton WS. Shain KH, et al. Expert Rev Hematol. 2009 Dec;2(6):649-62. doi: 10.1586/ehm.09.55. Expert Rev Hematol. 2009. PMID: 21082957 Review.

10

Monitoring a nuclear factor-κB signature of drug resistance in multiple myeloma.

Xiang Y, Remily-Wood ER, Oliveira V, Yarde D, He L, Cheng JQ, Mathews L, Boucher K, Cubitt C, Perez L, Gauthier TJ, Eschrich SA, Shain KH, Dalton WS, Hazlehurst L, Koomen JM. Xiang Y, et al. Among authors: shain kh. Mol Cell Proteomics. 2011 Nov;10(11):M110.005520. doi: 10.1074/mcp.M110.005520. Epub 2011 Aug 16. Mol Cell Proteomics. 2011. PMID: 21846842 Free PMC article.

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