Shanahan CM - Search Results

1

Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation.

Warren DT, Tajsic T, Mellad JA, Searles R, Zhang Q, Shanahan CM. Warren DT, et al. Among authors: shanahan cm. J Biol Chem. 2010 Jan 8;285(2):1311-20. doi: 10.1074/jbc.M109.032557. Epub 2009 Oct 27. J Biol Chem. 2010. PMID: 19861416 Free PMC article.

2

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

Zhang Q, Skepper JN, Yang F, Davies JD, Hegyi L, Roberts RG, Weissberg PL, Ellis JA, Shanahan CM. Zhang Q, et al. Among authors: shanahan cm. J Cell Sci. 2001 Dec;114(Pt 24):4485-98. doi: 10.1242/jcs.114.24.4485. J Cell Sci. 2001. PMID: 11792814

3

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

Zhang Q, Ragnauth C, Greener MJ, Shanahan CM, Roberts RG. Zhang Q, et al. Among authors: shanahan cm. Genomics. 2002 Nov;80(5):473-81. Genomics. 2002. PMID: 12408964

4

Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification.

Tyson KL, Reynolds JL, McNair R, Zhang Q, Weissberg PL, Shanahan CM. Tyson KL, et al. Among authors: shanahan cm. Arterioscler Thromb Vasc Biol. 2003 Mar 1;23(3):489-94. doi: 10.1161/01.ATV.0000059406.92165.31. Epub 2003 Jan 30. Arterioscler Thromb Vasc Biol. 2003. PMID: 12615658

5

Adipocytic differentiation and liver x receptor pathways regulate the accumulation of triacylglycerols in human vascular smooth muscle cells.

Davies JD, Carpenter KL, Challis IR, Figg NL, McNair R, Proudfoot D, Weissberg PL, Shanahan CM. Davies JD, et al. Among authors: shanahan cm. J Biol Chem. 2005 Feb 4;280(5):3911-9. doi: 10.1074/jbc.M410075200. Epub 2004 Nov 16. J Biol Chem. 2005. PMID: 15548517 Free article.

6

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle.

Zhang Q, Ragnauth CD, Skepper JN, Worth NF, Warren DT, Roberts RG, Weissberg PL, Ellis JA, Shanahan CM. Zhang Q, et al. Among authors: shanahan cm. J Cell Sci. 2005 Feb 15;118(Pt 4):673-87. doi: 10.1242/jcs.01642. Epub 2005 Jan 25. J Cell Sci. 2005. PMID: 15671068

7

Nesprins: intracellular scaffolds that maintain cell architecture and coordinate cell function?

Warren DT, Zhang Q, Weissberg PL, Shanahan CM. Warren DT, et al. Among authors: shanahan cm. Expert Rev Mol Med. 2005 Jun 13;7(11):1-15. doi: 10.1017/S1462399405009294. Expert Rev Mol Med. 2005. PMID: 15953398 Review.

8

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.

Wheeler MA, Davies JD, Zhang Q, Emerson LJ, Hunt J, Shanahan CM, Ellis JA. Wheeler MA, et al. Among authors: shanahan cm. Exp Cell Res. 2007 Aug 1;313(13):2845-57. doi: 10.1016/j.yexcr.2007.03.025. Epub 2007 Mar 30. Exp Cell Res. 2007. PMID: 17462627

9

Cell nuclei spin in the absence of lamin b1.

Ji JY, Lee RT, Vergnes L, Fong LG, Stewart CL, Reue K, Young SG, Zhang Q, Shanahan CM, Lammerding J. Ji JY, et al. Among authors: shanahan cm. J Biol Chem. 2007 Jul 6;282(27):20015-26. doi: 10.1074/jbc.M611094200. Epub 2007 May 8. J Biol Chem. 2007. PMID: 17488709 Free article.

10

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

Zhang Q, Bethmann C, Worth NF, Davies JD, Wasner C, Feuer A, Ragnauth CD, Yi Q, Mellad JA, Warren DT, Wheeler MA, Ellis JA, Skepper JN, Vorgerd M, Schlotter-Weigel B, Weissberg PL, Roberts RG, Wehnert M, Shanahan CM. Zhang Q, et al. Among authors: shanahan cm. Hum Mol Genet. 2007 Dec 1;16(23):2816-33. doi: 10.1093/hmg/ddm238. Epub 2007 Aug 29. Hum Mol Genet. 2007. PMID: 17761684

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