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Metformin increases degradation of phospholamban via autophagy in cardiomyocytes.
Teng AC, Miyake T, Yokoe S, Zhang L, Rezende LM Jr, Sharma P, MacLennan DH, Liu PP, Gramolini AO. Teng AC, et al. Among authors: sharma p. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7165-70. doi: 10.1073/pnas.1508815112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26040000 Free PMC article.
Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.
Gramolini AO, Kislinger T, Alikhani-Koopaei R, Fong V, Thompson NJ, Isserlin R, Sharma P, Oudit GY, Trivieri MG, Fagan A, Kannan A, Higgins DG, Huedig H, Hess G, Arab S, Seidman JG, Seidman CE, Frey B, Perry M, Backx PH, Liu PP, MacLennan DH, Emili A. Gramolini AO, et al. Among authors: sharma p. Mol Cell Proteomics. 2008 Mar;7(3):519-33. doi: 10.1074/mcp.M700245-MCP200. Epub 2007 Nov 30. Mol Cell Proteomics. 2008. PMID: 18056057 Free article.
REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.
Lee SH, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim S, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO. Lee SH, et al. Among authors: sharma p. Nat Commun. 2020 Feb 19;11(1):965. doi: 10.1038/s41467-019-14143-9. Nat Commun. 2020. PMID: 32075961 Free PMC article.
Clinical proteomics: getting to the heart of the matter.
Chugh S, Sharma P, Kislinger T, Gramolini AO. Chugh S, et al. Among authors: sharma p. Circ Cardiovasc Genet. 2012 Jun;5(3):377. doi: 10.1161/CIRCGENETICS.110.957761. Circ Cardiovasc Genet. 2012. PMID: 22715282 No abstract available.
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