Sharma PK - Search Results

1

Electrostatic basis for enzyme catalysis.

Warshel A, Sharma PK, Kato M, Xiang Y, Liu H, Olsson MH. Warshel A, et al. Among authors: sharma pk. Chem Rev. 2006 Aug;106(8):3210-35. doi: 10.1021/cr0503106. Chem Rev. 2006. PMID: 16895325 Review. No abstract available.

2

Modeling electrostatic effects in proteins.

Warshel A, Sharma PK, Kato M, Parson WW. Warshel A, et al. Among authors: sharma pk. Biochim Biophys Acta. 2006 Nov;1764(11):1647-76. doi: 10.1016/j.bbapap.2006.08.007. Epub 2006 Aug 25. Biochim Biophys Acta. 2006. PMID: 17049320 Review.

3

Electrostatic contributions to binding of transition state analogues can be very different from the corresponding contributions to catalysis: phenolates binding to the oxyanion hole of ketosteroid isomerase.

Warshel A, Sharma PK, Chu ZT, Aqvist J. Warshel A, et al. Among authors: sharma pk. Biochemistry. 2007 Feb 13;46(6):1466-76. doi: 10.1021/bi061752u. Biochemistry. 2007. PMID: 17279612

4

A new paradigm for electrostatic catalysis of radical reactions in vitamin B12 enzymes.

Sharma PK, Chu ZT, Olsson MH, Warshel A. Sharma PK, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9661-6. doi: 10.1073/pnas.0702238104. Epub 2007 May 21. Proc Natl Acad Sci U S A. 2007. PMID: 17517615 Free PMC article.

5

Simulating redox coupled proton transfer in cytochrome c oxidase: looking for the proton bottleneck.

Olsson MH, Sharma PK, Warshel A. Olsson MH, et al. Among authors: sharma pk. FEBS Lett. 2005 Apr 11;579(10):2026-34. doi: 10.1016/j.febslet.2005.02.051. FEBS Lett. 2005. PMID: 15811313 Free article.

6

What are the roles of substrate-assisted catalysis and proximity effects in peptide bond formation by the ribosome?

Sharma PK, Xiang Y, Kato M, Warshel A. Sharma PK, et al. Biochemistry. 2005 Aug 30;44(34):11307-14. doi: 10.1021/bi0509806. Biochemistry. 2005. PMID: 16114867

7

Electrostatic basis for the unidirectionality of the primary proton transfer in cytochrome c oxidase.

Pisliakov AV, Sharma PK, Chu ZT, Haranczyk M, Warshel A. Pisliakov AV, et al. Among authors: sharma pk. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7726-31. doi: 10.1073/pnas.0800580105. Epub 2008 May 28. Proc Natl Acad Sci U S A. 2008. PMID: 18509049 Free PMC article.

8

Ketosteroid isomerase provides further support for the idea that enzymes work by electrostatic preorganization.

Kamerlin SC, Sharma PK, Chu ZT, Warshel A. Kamerlin SC, et al. Among authors: sharma pk. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4075-80. doi: 10.1073/pnas.0914579107. Epub 2010 Feb 11. Proc Natl Acad Sci U S A. 2010. PMID: 20150513 Free PMC article.

9

The energetics of the primary proton transfer in bacteriorhodopsin revisited: it is a sequential light-induced charge separation after all.

Braun-Sand S, Sharma PK, Chu ZT, Pisliakov AV, Warshel A. Braun-Sand S, et al. Among authors: sharma pk. Biochim Biophys Acta. 2008 May;1777(5):441-52. doi: 10.1016/j.bbabio.2008.03.001. Epub 2008 Mar 14. Biochim Biophys Acta. 2008. PMID: 18387356 Free PMC article.

10

Why nature really chose phosphate.

Kamerlin SC, Sharma PK, Prasad RB, Warshel A. Kamerlin SC, et al. Among authors: sharma pk. Q Rev Biophys. 2013 Feb;46(1):1-132. doi: 10.1017/S0033583512000157. Epub 2013 Jan 15. Q Rev Biophys. 2013. PMID: 23318152 Free PMC article. Review.

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