Shavlakadze T - Search Results

1

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.

Egerman MA, Cadena SM, Gilbert JA, Meyer A, Nelson HN, Swalley SE, Mallozzi C, Jacobi C, Jennings LL, Clay I, Laurent G, Ma S, Brachat S, Lach-Trifilieff E, Shavlakadze T, Trendelenburg AU, Brack AS, Glass DJ. Egerman MA, et al. Among authors: shavlakadze t. Cell Metab. 2015 Jul 7;22(1):164-74. doi: 10.1016/j.cmet.2015.05.010. Epub 2015 May 19. Cell Metab. 2015. PMID: 26001423 Free PMC article.

2

An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis.

Li Z, Gilbert JA, Zhang Y, Zhang M, Qiu Q, Ramanujan K, Shavlakadze T, Eash JK, Scaramozza A, Goddeeris MM, Kirsch DG, Campbell KP, Brack AS, Glass DJ. Li Z, et al. Among authors: shavlakadze t. Dev Cell. 2012 Dec 11;23(6):1176-88. doi: 10.1016/j.devcel.2012.10.019. Epub 2012 Nov 21. Dev Cell. 2012. PMID: 23177649 Free PMC article.

3

Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology.

Shavlakadze T, Zhu J, Wang S, Zhou W, Morin B, Egerman MA, Fan L, Wang Y, Iartchouk O, Meyer A, Valdez RA, Mannick JB, Klickstein LB, Glass DJ. Shavlakadze T, et al. J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):845-852. doi: 10.1093/gerona/glx249. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29304191 Free PMC article.

4

Partial Inhibition of mTORC1 in Aged Rats Counteracts the Decline in Muscle Mass and Reverses Molecular Signaling Associated with Sarcopenia.

Joseph GA, Wang SX, Jacobs CE, Zhou W, Kimble GC, Tse HW, Eash JK, Shavlakadze T, Glass DJ. Joseph GA, et al. Among authors: shavlakadze t. Mol Cell Biol. 2019 Sep 11;39(19):e00141-19. doi: 10.1128/MCB.00141-19. Print 2019 Oct 1. Mol Cell Biol. 2019. PMID: 31308131 Free PMC article.

5

Shavlakadze T, Morris M, Fang J, Wang SX, Zhu J, Zhou W, Tse HW, Mondragon-Gonzalez R, Roma G, Glass DJ. Shavlakadze T, et al. Cell Rep. 2019 Sep 17;28(12):3263-3273.e3. doi: 10.1016/j.celrep.2019.08.043. Cell Rep. 2019. PMID: 31533046 Free article.

6

TORC1 inhibition enhances immune function and reduces infections in the elderly.

Mannick JB, Morris M, Hockey HP, Roma G, Beibel M, Kulmatycki K, Watkins M, Shavlakadze T, Zhou W, Quinn D, Glass DJ, Klickstein LB. Mannick JB, et al. Among authors: shavlakadze t. Sci Transl Med. 2018 Jul 11;10(449):eaaq1564. doi: 10.1126/scitranslmed.aaq1564. Sci Transl Med. 2018. PMID: 29997249 Clinical Trial.

7

The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients.

McAleavy M, Zhang Q, Ehmann PJ, Xu J, Wipperman MF, Ajithdoss D, Pan L, Wakai M, Simonson R, Gadi A, Oyejide A, Hamon SC, Boyapati A, Morton LG, Shavlakadze T, Kyratsous CA, Glass DJ. McAleavy M, et al. Among authors: shavlakadze t. Mol Cell Biol. 2022 Jan 20;42(1):e0046721. doi: 10.1128/MCB.00467-21. Epub 2021 Nov 1. Mol Cell Biol. 2022. PMID: 34723652 Free PMC article. Clinical Trial.

8

High mTORC1 signaling is maintained, while protein degradation pathways are perturbed in old murine skeletal muscles in the fasted state.

White Z, White RB, McMahon C, Grounds MD, Shavlakadze T. White Z, et al. Among authors: shavlakadze t. Int J Biochem Cell Biol. 2016 Sep;78:10-21. doi: 10.1016/j.biocel.2016.06.012. Epub 2016 Jun 22. Int J Biochem Cell Biol. 2016. PMID: 27343428

9

Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice.

Barns M, Gondro C, Tellam RL, Radley-Crabb HG, Grounds MD, Shavlakadze T. Barns M, et al. Among authors: shavlakadze t. Int J Biochem Cell Biol. 2014 Aug;53:174-85. doi: 10.1016/j.biocel.2014.04.025. Epub 2014 May 13. Int J Biochem Cell Biol. 2014. PMID: 24836906

10

Differential thiol oxidation of the signaling proteins Akt, PTEN or PP2A determines whether Akt phosphorylation is enhanced or inhibited by oxidative stress in C2C12 myotubes derived from skeletal muscle.

Tan PL, Shavlakadze T, Grounds MD, Arthur PG. Tan PL, et al. Among authors: shavlakadze t. Int J Biochem Cell Biol. 2015 May;62:72-9. doi: 10.1016/j.biocel.2015.02.015. Epub 2015 Feb 28. Int J Biochem Cell Biol. 2015. PMID: 25737250 Free article.

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