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Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice.
Bachurin SO, Shelkovnikova TA, Ustyugov AA, Peters O, Khritankova I, Afanasieva MA, Tarasova TV, Alentov II, Buchman VL, Ninkina NN. Bachurin SO, et al. Neurotox Res. 2012 Jul;22(1):33-42. doi: 10.1007/s12640-011-9299-y. Epub 2011 Dec 17. Neurotox Res. 2012. PMID: 22179976 Free PMC article.
Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.
Shelkovnikova TA, Peters OM, Deykin AV, Connor-Robson N, Robinson H, Ustyugov AA, Bachurin SO, Ermolkevich TG, Goldman IL, Sadchikova ER, Kovrazhkina EA, Skvortsova VI, Ling SC, Da Cruz S, Parone PA, Buchman VL, Ninkina NN. Shelkovnikova TA, et al. J Biol Chem. 2013 Aug 30;288(35):25266-25274. doi: 10.1074/jbc.M113.492017. Epub 2013 Jul 18. J Biol Chem. 2013. PMID: 23867462 Free PMC article.
Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif.
Robinson HK, Deykin AV, Bronovitsky EV, Ovchinnikov RK, Ustyugov AA, Shelkovnikova TA, Kukharsky MS, Ermolkevich TG, Goldman IL, Sadchikova ER, Kovrazhkina EA, Bachurin SO, Buchman VL, Ninkina NN. Robinson HK, et al. Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(5-6):402-9. doi: 10.3109/21678421.2015.1040994. Epub 2015 May 20. Amyotroph Lateral Scler Frontotemporal Degener. 2015. PMID: 25991062 Free PMC article.
Gamma-synuclein pathology in amyotrophic lateral sclerosis.
Peters OM, Shelkovnikova T, Highley JR, Cooper-Knock J, Hortobágyi T, Troakes C, Ninkina N, Buchman VL. Peters OM, et al. Among authors: shelkovnikova t. Ann Clin Transl Neurol. 2015 Jan;2(1):29-37. doi: 10.1002/acn3.143. Epub 2014 Dec 12. Ann Clin Transl Neurol. 2015. PMID: 25642432 Free PMC article.
55 results