Shen M - Search Results

1

A Combinatorial Strategy for Targeting BRAF ^V600E-Mutant Cancers with BRAF^V600E Inhibitor (PLX4720) and Tyrosine Kinase Inhibitor (Ponatinib).

Ghosh C, Kumar S, Kushchayeva Y, Gaskins K, Boufraqech M, Wei D, Gara SK, Zhang L, Zhang YQ, Shen M, Mukherjee S, Kebebew E. Ghosh C, et al. Among authors: shen m. Clin Cancer Res. 2020 Apr 15;26(8):2022-2036. doi: 10.1158/1078-0432.CCR-19-1606. Epub 2020 Jan 14. Clin Cancer Res. 2020. PMID: 31937621 Free PMC article.

2

Quantitative high-throughput drug screening identifies novel classes of drugs with anticancer activity in thyroid cancer cells: opportunities for repurposing.

Zhang L, He M, Zhang Y, Nilubol N, Shen M, Kebebew E. Zhang L, et al. Among authors: shen m. J Clin Endocrinol Metab. 2012 Mar;97(3):E319-28. doi: 10.1210/jc.2011-2671. Epub 2011 Dec 14. J Clin Endocrinol Metab. 2012. PMID: 22170715 Free PMC article.

3

Four clinically utilized drugs were identified and validated for treatment of adrenocortical cancer using quantitative high-throughput screening.

Nilubol N, Zhang L, Shen M, Zhang YQ, He M, Austin CP, Kebebew E. Nilubol N, et al. Among authors: shen m. J Transl Med. 2012 Sep 21;10:198. doi: 10.1186/1479-5876-10-198. J Transl Med. 2012. PMID: 22999104 Free PMC article.

4

TOP2A is overexpressed and is a therapeutic target for adrenocortical carcinoma.

Jain M, Zhang L, He M, Zhang YQ, Shen M, Kebebew E. Jain M, et al. Among authors: shen m. Endocr Relat Cancer. 2013 May 21;20(3):361-70. doi: 10.1530/ERC-12-0403. Print 2013 Jun. Endocr Relat Cancer. 2013. PMID: 23533247 Free PMC article.

5

Identification of therapeutic candidates for chronic lymphocytic leukemia from a library of approved drugs.

Shen M, Zhang Y, Saba N, Austin CP, Wiestner A, Auld DS. Shen M, et al. PLoS One. 2013 Sep 20;8(9):e75252. doi: 10.1371/journal.pone.0075252. eCollection 2013. PLoS One. 2013. PMID: 24073257 Free PMC article.

6

Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia.

Fiskus W, Saba N, Shen M, Ghias M, Liu J, Gupta SD, Chauhan L, Rao R, Gunewardena S, Schorno K, Austin CP, Maddocks K, Byrd J, Melnick A, Huang P, Wiestner A, Bhalla KN. Fiskus W, et al. Among authors: shen m. Cancer Res. 2014 May 1;74(9):2520-32. doi: 10.1158/0008-5472.CAN-13-2033. Epub 2014 Mar 5. Cancer Res. 2014. PMID: 24599128 Free PMC article.

7

High-throughput screening for the identification of new therapeutic options for metastatic pheochromocytoma and paraganglioma.

Giubellino A, Shankavaram U, Bullova P, Schovanek J, Zhang Y, Shen M, Patel N, Elkahloun A, Lee MJ, Trepel J, Ferrer M, Pacak K. Giubellino A, et al. Among authors: shen m. PLoS One. 2014 Apr 3;9(4):e90458. doi: 10.1371/journal.pone.0090458. eCollection 2014. PLoS One. 2014. PMID: 24699253 Free PMC article.

8

Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer.

Zhang L, Zhang Y, Mehta A, Boufraqech M, Davis S, Wang J, Tian Z, Yu Z, Boxer MB, Kiefer JA, Copland JA, Smallridge RC, Li Z, Shen M, Kebebew E. Zhang L, et al. Among authors: shen m. Oncotarget. 2015 Apr 20;6(11):9073-85. doi: 10.18632/oncotarget.3268. Oncotarget. 2015. PMID: 25940539 Free PMC article.

9

Inhibition of Survivin with YM155 Induces Durable Tumor Response in Anaplastic Thyroid Cancer.

Mehta A, Zhang L, Boufraqech M, Liu-Chittenden Y, Zhang Y, Patel D, Davis S, Rosenberg A, Ylaya K, Aufforth R, Li Z, Shen M, Kebebew E. Mehta A, et al. Among authors: shen m. Clin Cancer Res. 2015 Sep 15;21(18):4123-32. doi: 10.1158/1078-0432.CCR-14-3251. Epub 2015 May 5. Clin Cancer Res. 2015. PMID: 25944801 Free PMC article.

10

Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis.

Sadowski SM, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, Li Z, Shen M, Kebebew E. Sadowski SM, et al. Among authors: shen m. Oncotarget. 2015 Jul 20;6(20):18038-49. doi: 10.18632/oncotarget.3833. Oncotarget. 2015. PMID: 25945839 Free PMC article.

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