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Topical Anti-TNFα Agent Licaminlimab (OCS-02) Relieves Persistent Ocular Discomfort in Severe Dry Eye Disease: A Randomized Phase II Study.
Clin Ophthalmol. 2022 Jul 6;16:2167-2177. doi: 10.2147/OPTH.S366836. eCollection 2022.
Clin Ophthalmol. 2022.
PMID: 35821785
Free PMC article.
Clinical Trial.
Clinical Outcomes of Fixed Versus As-Needed Use of Artificial Tears in Dry Eye Disease: A 6-Week, Observer-Masked Phase 4 Clinical Trial.
Asbell P, Vingrys AJ, Tan J, Ogundele A, Downie LE, Jerkins G, Shettle L.
Asbell P, et al. Among authors: shettle l.
Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2275-2280. doi: 10.1167/iovs.17-23733.
Invest Ophthalmol Vis Sci. 2018.
PMID: 29715369
Clinical Trial.
Item in Clipboard
Effect of OTX-101, a Novel Nanomicellar Formulation of Cyclosporine A, on Corneal Staining in Patients With Keratoconjunctivitis Sicca: A Pooled Analysis of Phase 2b/3 and Phase 3 Studies.
Malhotra R, Devries DK, Luchs J, Kabat A, Schechter BA, Shen Lee B, Shettle L, Smyth-Medina R, Ogundele A, Darby C, Bacharach J, Karpecki P.
Malhotra R, et al. Among authors: shettle l.
Cornea. 2019 Oct;38(10):1259-1265. doi: 10.1097/ICO.0000000000001989.
Cornea. 2019.
PMID: 31306284
Free PMC article.
Clinical Trial.
Item in Clipboard
Impact of Dry Eye Disease on Work Productivity, and Patients' Satisfaction With Over-the-Counter Dry Eye Treatments.
Nichols KK, Bacharach J, Holland E, Kislan T, Shettle L, Lunacsek O, Lennert B, Burk C, Patel V.
Nichols KK, et al. Among authors: shettle l.
Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):2975-82. doi: 10.1167/iovs.16-19419.
Invest Ophthalmol Vis Sci. 2016.
PMID: 27273596
Item in Clipboard
Conjunctival concentrations of a new ophthalmic solution formulation of moxifloxacin 0.5% in cataract surgery patients.
Lindstrom R, Lane S, Cottingham A, Smith S, Sall K, Silverstein S, Shettle L, Walters T, Faulkner R, Cockrum P, Teuscher N.
Lindstrom R, et al. Among authors: shettle l.
J Ocul Pharmacol Ther. 2010 Dec;26(6):591-5. doi: 10.1089/jop.2010.0089. Epub 2010 Oct 6.
J Ocul Pharmacol Ther. 2010.
PMID: 20925517
Clinical Trial.
Item in Clipboard
n-3 Fatty Acid Supplementation for the Treatment of Dry Eye Disease.
Dry Eye Assessment and Management Study Research Group; Asbell PA, Maguire MG, Pistilli M, Ying GS, Szczotka-Flynn LB, Hardten DR, Lin MC, Shtein RM.
Dry Eye Assessment and Management Study Research Group, et al.
N Engl J Med. 2018 May 3;378(18):1681-1690. doi: 10.1056/NEJMoa1709691. Epub 2018 Apr 13.
N Engl J Med. 2018.
PMID: 29652551
Free PMC article.
Clinical Trial.
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