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Structure of the trypanosome cyanide-insensitive alternative oxidase.
Shiba T, Kido Y, Sakamoto K, Inaoka DK, Tsuge C, Tatsumi R, Takahashi G, Balogun EO, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Saimoto H, Moore AL, Harada S, Kita K. Shiba T, et al. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4580-5. doi: 10.1073/pnas.1218386110. Epub 2013 Mar 4. Proc Natl Acad Sci U S A. 2013. PMID: 23487766 Free PMC article.
Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidase from Trypanosoma brucei brucei.
Kido Y, Shiba T, Inaoka DK, Sakamoto K, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Moore A, Harada S, Kita K. Kido Y, et al. Among authors: shiba t. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):275-8. doi: 10.1107/S1744309109054062. Epub 2010 Feb 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20208159 Free PMC article.
Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic 4-hydroxybenzoate and 4-alkoxybenzaldehyde derivatives active against T. brucei and T. congolense.
Ebiloma GU, Ayuga TD, Balogun EO, Gil LA, Donachie A, Kaiser M, Herraiz T, Inaoka DK, Shiba T, Harada S, Kita K, de Koning HP, Dardonville C. Ebiloma GU, et al. Among authors: shiba t. Eur J Med Chem. 2018 Apr 25;150:385-402. doi: 10.1016/j.ejmech.2018.02.075. Epub 2018 Feb 26. Eur J Med Chem. 2018. PMID: 29544150 Free article.
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.
Balogun EO, Inaoka DK, Shiba T, Tsuge C, May B, Sato T, Kido Y, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PAM, Watanabe YI, Moore AL, Harada S, Kita K. Balogun EO, et al. Among authors: shiba t. FASEB J. 2019 Nov;33(11):13002-13013. doi: 10.1096/fj.201901342R. Epub 2019 Sep 16. FASEB J. 2019. PMID: 31525300
Although the EC(50) of compound 17b against trypanosome cells was 1.77 M, it had no effect on cultured human cells, even at 50 M.-Balogun, E. O., Inaoka, D. K., Shiba, T., Tsuge, C., May, B., Sato, T., Kido, Y., Nara, T., Aoki, T., Honma, T …
Although the EC(50) of compound 17b against trypanosome cells was 1.77 M, it had no effect on cultured human cells, even at 50 M.-Balogun, E …
Overproduction, purification, crystallization and preliminary X-ray diffraction analysis of Trypanosoma brucei gambiense glycerol kinase.
Balogun EO, Inaoka DK, Kido Y, Shiba T, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PA, Harada S, Kita K. Balogun EO, et al. Among authors: shiba t. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):304-8. doi: 10.1107/S1744309110000369. Epub 2010 Feb 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20208167 Free PMC article.
798 results