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Catalytic in vivo protein knockdown by small-molecule PROTACs.
Bondeson DP, Mares A, Smith IE, Ko E, Campos S, Miah AH, Mulholland KE, Routly N, Buckley DL, Gustafson JL, Zinn N, Grandi P, Shimamura S, Bergamini G, Faelth-Savitski M, Bantscheff M, Cox C, Gordon DA, Willard RR, Flanagan JJ, Casillas LN, Votta BJ, den Besten W, Famm K, Kruidenier L, Carter PS, Harling JD, Churcher I, Crews CM. Bondeson DP, et al. Among authors: shimamura s. Nat Chem Biol. 2015 Aug;11(8):611-7. doi: 10.1038/nchembio.1858. Epub 2015 Jun 10. Nat Chem Biol. 2015. PMID: 26075522 Free PMC article.
A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation.
Bergamini G, Bell K, Shimamura S, Werner T, Cansfield A, Müller K, Perrin J, Rau C, Ellard K, Hopf C, Doce C, Leggate D, Mangano R, Mathieson T, O'Mahony A, Plavec I, Rharbaoui F, Reinhard F, Savitski MM, Ramsden N, Hirsch E, Drewes G, Rausch O, Bantscheff M, Neubauer G. Bergamini G, et al. Among authors: shimamura s. Nat Chem Biol. 2012 Apr 29;8(6):576-82. doi: 10.1038/nchembio.957. Nat Chem Biol. 2012. PMID: 22544264
Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).
Bulatov E, Martin EM, Chatterjee S, Knebel A, Shimamura S, Konijnenberg A, Johnson C, Zinn N, Grandi P, Sobott F, Ciulli A. Bulatov E, et al. Among authors: shimamura s. J Biol Chem. 2015 Feb 13;290(7):4178-91. doi: 10.1074/jbc.M114.616664. Epub 2014 Dec 11. J Biol Chem. 2015. PMID: 25505247 Free PMC article.
Hyperprogressive disease under anti-PD-1 rechallenge after initial response to anti-PD-1 treatment for non-small cell lung cancer: a case report.
Xu S, Shukuya T, Shimamura S, Hayashi T, Sato Y, Shiozaki H, Nishioki T, Nishino K, Kato M, Hattori A, Shimada N, Suzuki K, Kitano S, Takahashi K. Xu S, et al. Among authors: shimamura s. Transl Lung Cancer Res. 2024 Mar 29;13(3):666-672. doi: 10.21037/tlcr-23-765. Epub 2024 Mar 27. Transl Lung Cancer Res. 2024. PMID: 38601437 Free PMC article.
Removal of phosphoglycolate in hyperthermophilic archaea.
Michimori Y, Izaki R, Su Y, Fukuyama Y, Shimamura S, Nishimura K, Miwa Y, Hamakita S, Shimosaka T, Makino Y, Takeno R, Sato T, Beppu H, Cann I, Kanai T, Nunoura T, Atomi H. Michimori Y, et al. Among authors: shimamura s. Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2311390121. doi: 10.1073/pnas.2311390121. Epub 2024 Apr 9. Proc Natl Acad Sci U S A. 2024. PMID: 38593075
275 results