Shin KJ - Search Results

1

Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors.

Kim S, Jung JK, Lee HS, Kim Y, Kim J, Choi K, Baek DJ, Moon B, Oh KS, Lee BH, Shin KJ, Pae AN, Nam G, Roh EJ, Cho YS, Choo H. Kim S, et al. Among authors: shin kj. Bioorg Med Chem Lett. 2011 May 15;21(10):3002-6. doi: 10.1016/j.bmcl.2011.03.044. Epub 2011 Mar 17. Bioorg Med Chem Lett. 2011. PMID: 21489792

2

Synthesis and evaluation of alpha,alpha'-disubstituted phenylacetate derivatives for T-type calcium channel blockers.

Lee HK, Lee YS, Roh EJ, Rhim H, Lee JY, Shin KJ. Lee HK, et al. Among authors: shin kj. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4424-7. doi: 10.1016/j.bmcl.2008.06.037. Epub 2008 Jun 14. Bioorg Med Chem Lett. 2008. PMID: 18625556

3

IKKbeta inhibitors identification part II: ligand and structure-based virtual screening.

Nagarajan S, Choo H, Cho YS, Oh KS, Lee BH, Shin KJ, Pae AN. Nagarajan S, et al. Among authors: shin kj. Bioorg Med Chem. 2010 Jun 1;18(11):3951-60. doi: 10.1016/j.bmc.2010.04.030. Epub 2010 Apr 18. Bioorg Med Chem. 2010. PMID: 20488717

4

IKKβ inhibitor identification: a multi-filter driven novel scaffold.

Nagarajan S, Choo H, Cho YS, Shin KJ, Oh KS, Lee BH, Pae AN. Nagarajan S, et al. Among authors: shin kj. BMC Bioinformatics. 2010 Oct 15;11 Suppl 7(Suppl 7):S15. doi: 10.1186/1471-2105-11-S7-S15. BMC Bioinformatics. 2010. PMID: 21106122 Free PMC article.

5

Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers.

Woo HM, Lee YS, Roh EJ, Seo SH, Song CM, Chung HJ, Pae AN, Shin KJ. Woo HM, et al. Among authors: shin kj. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5910-5. doi: 10.1016/j.bmcl.2011.07.087. Epub 2011 Jul 29. Bioorg Med Chem Lett. 2011. PMID: 21843937

6

Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid.

Lee YS, Kim HY, Kim Y, Seo JH, Roh EJ, Han H, Shin KJ. Lee YS, et al. Among authors: shin kj. Bioorg Med Chem. 2012 Aug 15;20(16):4921-35. doi: 10.1016/j.bmc.2012.06.045. Epub 2012 Jul 3. Bioorg Med Chem. 2012. PMID: 22831802

7

Discovery of potent and selective rhodanine type IKKβ inhibitors by hit-to-lead strategy.

Song H, Lee YS, Roh EJ, Seo JH, Oh KS, Lee BH, Han H, Shin KJ. Song H, et al. Among authors: shin kj. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5668-74. doi: 10.1016/j.bmcl.2012.06.088. Epub 2012 Jul 15. Bioorg Med Chem Lett. 2012. PMID: 22858099

8

Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's disease.

Lee YS, Kim H, Kim YH, Roh EJ, Han H, Shin KJ. Lee YS, et al. Among authors: shin kj. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7555-61. doi: 10.1016/j.bmcl.2012.10.022. Epub 2012 Oct 13. Bioorg Med Chem Lett. 2012. PMID: 23140885

9

Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-β modulators.

Elkamhawy A, Kim NY, Hassan AHE, Park JE, Yang JE, Oh KS, Lee BH, Lee MY, Shin KJ, Lee KT, Hur W, Roh EJ. Elkamhawy A, et al. Among authors: shin kj. Eur J Med Chem. 2018 Sep 5;157:691-704. doi: 10.1016/j.ejmech.2018.08.020. Epub 2018 Aug 8. Eur J Med Chem. 2018. PMID: 30130718

10

Optimization study towards more potent thiazolidine-2,4-dione IKK-β modulator: Synthesis, biological evaluation and in silico docking simulation.

Elkamhawy A, Youn Kim N, Hassan AHE, Park JE, Yang JE, Elsherbeny MH, Paik S, Oh KS, Lee BH, Lee MY, Shin KJ, Pae AN, Lee KT, Roh EJ. Elkamhawy A, et al. Among authors: shin kj. Bioorg Chem. 2019 Nov;92:103261. doi: 10.1016/j.bioorg.2019.103261. Epub 2019 Sep 7. Bioorg Chem. 2019. PMID: 31542718

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