Shindoh H - Search Results

1

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 3.

Kawasaki K, Masubuchi M, Morikami K, Sogabe S, Aoyama T, Ebiike H, Niizuma S, Hayase M, Fujii T, Sakata K, Shindoh H, Shiratori Y, Aoki Y, Ohtsuka T, Shimma N. Kawasaki K, et al. Among authors: shindoh h. Bioorg Med Chem Lett. 2003 Jan 6;13(1):87-91. doi: 10.1016/s0960-894x(02)00844-2. Bioorg Med Chem Lett. 2003. PMID: 12467623

2

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2.

Ebiike H, Masubuchi M, Liu P, Kawasaki K, Morikami K, Sogabe S, Hayase M, Fujii T, Sakata K, Shindoh H, Shiratori Y, Aoki Y, Ohtsuka T, Shimma N. Ebiike H, et al. Among authors: shindoh h. Bioorg Med Chem Lett. 2002 Feb 25;12(4):607-10. doi: 10.1016/s0960-894x(01)00808-3. Bioorg Med Chem Lett. 2002. PMID: 11844682

3

Cassette dosing approach and quantitative structure-pharmacokinetic relationship study of antifungal N-myristoyltransferase inhibitors.

Hasegawa K, Shindoh H, Shiratori Y, Ohtsuka T, Aoki Y, Ichihara S, Horii I, Shimma N. Hasegawa K, et al. Among authors: shindoh h. J Chem Inf Comput Sci. 2002 Jul-Aug;42(4):968-75. doi: 10.1021/ci0102517. J Chem Inf Comput Sci. 2002. PMID: 12132899

4

Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase.

Masubuchi M, Ebiike H, Kawasaki K, Sogabe S, Morikami K, Shiratori Y, Tsujii S, Fujii T, Sakata K, Hayase M, Shindoh H, Aoki Y, Ohtsuka T, Shimma N. Masubuchi M, et al. Among authors: shindoh h. Bioorg Med Chem. 2003 Oct 1;11(20):4463-78. doi: 10.1016/s0968-0896(03)00429-2. Bioorg Med Chem. 2003. PMID: 13129583

5

Enantioselective synthesis of derivatives and structure-activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent.

Kawasaki K, Masubuchi M, Hayase T, Komiyama S, Watanabe F, Fukuda H, Murata T, Matsubara Y, Koyama K, Shindoh H, Sakamoto H, Okamato K, Ohta A, Katsume A, Aoki M, Aoki Y, Shimma N, Sudoh M, Tsukuda T. Kawasaki K, et al. Among authors: shindoh h. Bioorg Med Chem Lett. 2013 Jan 1;23(1):336-9. doi: 10.1016/j.bmcl.2012.10.083. Epub 2012 Oct 30. Bioorg Med Chem Lett. 2013. PMID: 23164713

6

Discovery of [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor.

Ebiike H, Taka N, Matsushita M, Ohmori M, Takami K, Hyohdoh I, Kohchi M, Hayase T, Nishii H, Morikami K, Nakanishi Y, Akiyama N, Shindoh H, Ishii N, Isobe T, Matsuoka H. Ebiike H, et al. Among authors: shindoh h. J Med Chem. 2016 Dec 8;59(23):10586-10600. doi: 10.1021/acs.jmedchem.6b01156. Epub 2016 Nov 29. J Med Chem. 2016. PMID: 27933954

7

The fibroblast growth factor receptor genetic status as a potential predictor of the sensitivity to CH5183284/Debio 1347, a novel selective FGFR inhibitor.

Nakanishi Y, Akiyama N, Tsukaguchi T, Fujii T, Sakata K, Sase H, Isobe T, Morikami K, Shindoh H, Mio T, Ebiike H, Taka N, Aoki Y, Ishii N. Nakanishi Y, et al. Among authors: shindoh h. Mol Cancer Ther. 2014 Nov;13(11):2547-58. doi: 10.1158/1535-7163.MCT-14-0248. Epub 2014 Aug 28. Mol Cancer Ther. 2014. PMID: 25169980

8

Estimating the clinical risk of hypertension from VEGF signal inhibitors by a non-clinical approach using telemetered rats.

Isobe T, Komatsu R, Honda M, Kuramoto S, Shindoh H, Tabo M. Isobe T, et al. Among authors: shindoh h. J Toxicol Sci. 2014 Apr;39(2):237-42. doi: 10.2131/jts.39.237. J Toxicol Sci. 2014. PMID: 24646704 Free article.

9

Advantages of in vitro cytotoxicity testing by using primary rat hepatocytes in comparison with established cell lines.

Wang K, Shindoh H, Inoue T, Horii I. Wang K, et al. Among authors: shindoh h. J Toxicol Sci. 2002 Aug;27(3):229-37. doi: 10.2131/jts.27.229. J Toxicol Sci. 2002. PMID: 12238146 Free article.

10

Relationship between AUC of 5'-DFUR and toxicity of capecitabine, fluoropyrimidine carbamate analogs, and 5'-DFUR in monkeys, mice, and rats.

Shindoh H, Kawashima A, Shishido N, Nakano K, Kobayashi K, Horii I. Shindoh H, et al. J Toxicol Sci. 2006 Aug;31(3):265-85. doi: 10.2131/jts.31.265. J Toxicol Sci. 2006. PMID: 16960436 Free article.

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