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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems.
Shmakov S, Abudayyeh OO, Makarova KS, Wolf YI, Gootenberg JS, Semenova E, Minakhin L, Joung J, Konermann S, Severinov K, Zhang F, Koonin EV. Shmakov S, et al. Mol Cell. 2015 Nov 5;60(3):385-97. doi: 10.1016/j.molcel.2015.10.008. Epub 2015 Oct 22. Mol Cell. 2015. PMID: 26593719 Free PMC article.
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.
Abudayyeh OO, Gootenberg JS, Konermann S, Joung J, Slaymaker IM, Cox DB, Shmakov S, Makarova KS, Semenova E, Minakhin L, Severinov K, Regev A, Lander ES, Koonin EV, Zhang F. Abudayyeh OO, et al. Science. 2016 Aug 5;353(6299):aaf5573. doi: 10.1126/science.aaf5573. Epub 2016 Jun 2. Science. 2016. PMID: 27256883 Free PMC article.
Altered stoichiometry Escherichia coli Cascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation.
Kuznedelov K, Mekler V, Lemak S, Tokmina-Lukaszewska M, Datsenko KA, Jain I, Savitskaya E, Mallon J, Shmakov S, Bothner B, Bailey S, Yakunin AF, Severinov K, Semenova E. Kuznedelov K, et al. Nucleic Acids Res. 2016 Dec 15;44(22):10849-10861. doi: 10.1093/nar/gkw914. Epub 2016 Oct 13. Nucleic Acids Res. 2016. PMID: 27738137 Free PMC article.
Dynamics of Escherichia coli type I-E CRISPR spacers over 42 000 years.
Savitskaya E, Lopatina A, Medvedeva S, Kapustin M, Shmakov S, Tikhonov A, Artamonova II, Logacheva M, Severinov K. Savitskaya E, et al. Mol Ecol. 2017 Apr;26(7):2019-2026. doi: 10.1111/mec.13961. Epub 2017 Jan 17. Mol Ecol. 2017. PMID: 27997045 Free PMC article.
Diversity and evolution of class 2 CRISPR-Cas systems.
Shmakov S, Smargon A, Scott D, Cox D, Pyzocha N, Yan W, Abudayyeh OO, Gootenberg JS, Makarova KS, Wolf YI, Severinov K, Zhang F, Koonin EV. Shmakov S, et al. Nat Rev Microbiol. 2017 Mar;15(3):169-182. doi: 10.1038/nrmicro.2016.184. Epub 2017 Jan 23. Nat Rev Microbiol. 2017. PMID: 28111461 Free PMC article.
34 results