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Validation of ELISA methods for quantification of total tau and phosporylated-tau181 in human cerebrospinal fluid with measurement in specimens from two Alzheimer's disease studies.
Lachno DR, Romeo MJ, Siemers ER, Vanderstichele H, Coart E, Konrad RJ, Zajac JJ, Talbot JA, Jensen HF, Sethuraman G, Demattos RB, May PC, Dean RA. Lachno DR, et al. Among authors: siemers er. J Alzheimers Dis. 2011;26(3):531-41. doi: 10.3233/JAD-2011-110296. J Alzheimers Dis. 2011. PMID: 21694458
Comparison of pharmacokinetics, pharmacodynamics, safety, and tolerability of the amyloid β monoclonal antibody solanezumab in Japanese and white patients with mild to moderate alzheimer disease.
Uenaka K, Nakano M, Willis BA, Friedrich S, Ferguson-Sells L, Dean RA, Ieiri I, Siemers ER. Uenaka K, et al. Among authors: siemers er. Clin Neuropharmacol. 2012 Jan-Feb;35(1):25-9. doi: 10.1097/WNF.0b013e31823a13d3. Clin Neuropharmacol. 2012. PMID: 22134132 Clinical Trial.
Safety and biomarker effects of solanezumab in patients with Alzheimer's disease.
Farlow M, Arnold SE, van Dyck CH, Aisen PS, Snider BJ, Porsteinsson AP, Friedrich S, Dean RA, Gonzales C, Sethuraman G, DeMattos RB, Mohs R, Paul SM, Siemers ER. Farlow M, et al. Among authors: siemers er. Alzheimers Dement. 2012 Jul;8(4):261-71. doi: 10.1016/j.jalz.2011.09.224. Epub 2012 Jun 5. Alzheimers Dement. 2012. PMID: 22672770 Clinical Trial.
150 results