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Did you mean siglec (5,913 results)?
Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.
Kim DW, Tu KJ, Wei A, Lau AJ, Gonzalez-Gil A, Cao T, Braunstein K, Ling JP, Troncoso JC, Wong PC, Blackshaw S, Schnaar RL, Li T. Kim DW, et al. Mol Neurodegener. 2022 Dec 17;17(1):83. doi: 10.1186/s13024-022-00589-x. Mol Neurodegener. 2022. PMID: 36536457 Free PMC article.
Furthermore, we show that several Siglec genes are selectively expressed in either EADAM or LADAM. Siglecg is expressed in white-matter-associated LADAM, and expression of Siglec-10, the human orthologue of Siglecg, is progressively elevated in an AD-stage-dependent …
Furthermore, we show that several Siglec genes are selectively expressed in either EADAM or LADAM. Siglecg is expressed in white-matt …
Epistatic effects of Siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus.
Korn MA, Steffensen M, Brandl C, Royzman D, Daniel C, Winkler TH, Nitschke L. Korn MA, et al. Front Immunol. 2023 Mar 8;14:1095830. doi: 10.3389/fimmu.2023.1095830. eCollection 2023. Front Immunol. 2023. PMID: 36969253 Free PMC article.
Here, we analyze the development of SLE-like symptoms in mice deficient in either Siglecg and DNase1 or Siglecg and DNase1l3 to evaluate potential epistatic effects of these genes. ...Histological analysis of the kidneys revealed glomerulonephritis in both Siglec …
Here, we analyze the development of SLE-like symptoms in mice deficient in either Siglecg and DNase1 or Siglecg and DNase1l3 t …
Siglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activation.
Ding C, Liu Y, Wang Y, Park BK, Wang CY, Zheng P, Liu Y. Ding C, et al. PLoS One. 2007 Oct 3;2(10):e997. doi: 10.1371/journal.pone.0000997. PLoS One. 2007. PMID: 17912374 Free PMC article.
How this lineage is genetically determined remained largely obscure. METHODS AND PRINCIPAL FINDINGS: Using the Siglecg-deficient mice with a knockin of green-fluorescent protein encoding sequence, we show here that, although the Siglecg gene is broadly expressed at …
How this lineage is genetically determined remained largely obscure. METHODS AND PRINCIPAL FINDINGS: Using the Siglecg-deficient mice …
Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction.
Chen GY, Chen X, King S, Cavassani KA, Cheng J, Zheng X, Cao H, Yu H, Qu J, Fang D, Wu W, Bai XF, Liu JQ, Woodiga SA, Chen C, Sun L, Hogaboam CM, Kunkel SL, Zheng P, Liu Y. Chen GY, et al. Nat Biotechnol. 2011 May;29(5):428-35. doi: 10.1038/nbt.1846. Epub 2011 Apr 10. Nat Biotechnol. 2011. PMID: 21478876 Free PMC article.
In mice, inflammatory responses to host danger-associated molecular patterns (DAMPs), but not to microbial pathogen-associated molecular patterns (PAMPs), are repressed by the interaction [corrected] of CD24 and SiglecG (SIGLEC10 in human). Here we use an intestinal perfor …
In mice, inflammatory responses to host danger-associated molecular patterns (DAMPs), but not to microbial pathogen-associated molecular pat …
Sialic acids and autoimmune disease.
Mahajan VS, Pillai S. Mahajan VS, et al. Immunol Rev. 2016 Jan;269(1):145-61. doi: 10.1111/imr.12344. Immunol Rev. 2016. PMID: 26683151 Free PMC article. Review.
62 results