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Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation.
Larder R, Sim MFM, Gulati P, Antrobus R, Tung YCL, Rimmington D, Ayuso E, Polex-Wolf J, Lam BYH, Dias C, Logan DW, Virtue S, Bosch F, Yeo GSH, Saudek V, O'Rahilly S, Coll AP. Larder R, et al. Among authors: sim mfm. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):9421-9426. doi: 10.1073/pnas.1707310114. Epub 2017 Aug 15. Proc Natl Acad Sci U S A. 2017. PMID: 28811369 Free PMC article.
Discovering metabolic disease gene interactions by correlated effects on cellular morphology.
Jiao Y, Ahmed U, Sim MFM, Bejar A, Zhang X, Talukder MMU, Rice R, Flannick J, Podgornaia AI, Reilly DF, Engreitz JM, Kost-Alimova M, Hartland K, Mercader JM, Georges S, Wagh V, Tadin-Strapps M, Doench JG, Edwardson JM, Rochford JJ, Rosen ED, Majithia AR. Jiao Y, et al. Among authors: sim mfm. Mol Metab. 2019 Jun;24:108-119. doi: 10.1016/j.molmet.2019.03.001. Epub 2019 Mar 13. Mol Metab. 2019. PMID: 30940487 Free PMC article.
HOXC10 Suppresses Browning to Maintain White Adipocyte Identity.
Tan HYA, Sim MFM, Tan SX, Ng Y, Gan SY, Li H, Neo SP, Gunaratne J, Xu F, Han W. Tan HYA, et al. Among authors: sim mfm. Diabetes. 2021 Aug;70(8):1654-1663. doi: 10.2337/db21-0114. Epub 2021 May 14. Diabetes. 2021. PMID: 33990396 Free PMC article.