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Traditional use and scientific investigations of the medicinal plant Simaba cedron Planch.
Helmstädter A. Helmstädter A. Pharmazie. 2019 Jul 1;74(7):385-389. doi: 10.1691/ph.2019.9490. Pharmazie. 2019. PMID: 31288893 Review.
Simaba cedron Planch (Simaroubaceae) has frequently been reported as a traditional remedy against snake bites, malaria, gastrointestinal and other disorders. ...An effect against snake-bites seems questionable, research about the usefulness against gastrointe
Simaba cedron Planch (Simaroubaceae) has frequently been reported as a traditional remedy against snake bites, malaria,
Simaba Cedron in Intermittent Fever.
[No authors listed] [No authors listed] Buffalo Med J Mon Rev Med Surg Sci. 1855 Apr;10(11):672. Buffalo Med J Mon Rev Med Surg Sci. 1855. PMID: 35375856 Free PMC article. No abstract available.
Cytotoxic quassinoids from Simaba cedron.
Ozeki A, Hitotsuyanagi Y, Hashimoto E, Itokawa H, Takeya K, de Mello Alves S. Ozeki A, et al. J Nat Prod. 1998 Jun 26;61(6):776-80. doi: 10.1021/np980023f. J Nat Prod. 1998. PMID: 9644063
Four new quassinoids, cedronolactones A-D (1-4), together with nine known compounds, simalikalactone D (5), chaparrinone (6), chaparrin (7), glaucarubolone (8), glaucarubol (9), samaderine Z (10), guanepolide (11), ailanquassin A (12), and polyandrol (13), were isolated from the …
Four new quassinoids, cedronolactones A-D (1-4), together with nine known compounds, simalikalactone D (5), chaparrinone (6), chaparrin (7), …
Cedronolactone E, a novel C(19) quassinoid from Simaba cedron.
Hitotsuyanagi Y, Ozeki A, Itokawa H, de Mello Alves S, Takeya K. Hitotsuyanagi Y, et al. J Nat Prod. 2001 Dec;64(12):1583-4. doi: 10.1021/np010364k. J Nat Prod. 2001. PMID: 11754621
A novel pentacyclic C(19) quassinoid, cedronolactone E (1), was isolated from the wood of Simaba cedron. Its structure was elucidated by interpretation of spectroscopic data....
A novel pentacyclic C(19) quassinoid, cedronolactone E (1), was isolated from the wood of Simaba cedron. Its structure was elu …
Medicinal plants used to treat snakebite in Central America: Review and assessment of scientific evidence.
Giovannini P, Howes MR. Giovannini P, et al. J Ethnopharmacol. 2017 Mar 6;199:240-256. doi: 10.1016/j.jep.2017.02.011. Epub 2017 Feb 4. J Ethnopharmacol. 2017. PMID: 28179114 Review.
., Dorstenia contrajerva L., Scoparia dulcis L., Hamelia patens Jacq., and Simaba cedron Planch. Genera with the highest number of species used to treat snakebite were Piper, Aristolochia, Hamelia, Ipomoea, Passiflora and Peperomia. ...
., Dorstenia contrajerva L., Scoparia dulcis L., Hamelia patens Jacq., and Simaba cedron Planch. Genera with the highest numbe …
Ethnopharmacological evaluation of medicinal plants used against malaria by quilombola communities from Oriximiná, Brazil.
Oliveira DR, Krettli AU, Aguiar AC, Leitão GG, Vieira MN, Martins KS, Leitão SG. Oliveira DR, et al. J Ethnopharmacol. 2015 Sep 15;173:424-34. doi: 10.1016/j.jep.2015.07.035. Epub 2015 Jul 29. J Ethnopharmacol. 2015. PMID: 26231451 Free article.
The most active plant extracts, with an IC50 as low as 1.6mug/mL, were obtained from Aspidosperma rigidum (Apocynaceae), Bertholletia excelsa (Lecythidaceae) and Simaba cedron (Simaroubaceae), all of which displayed an S value>1. ...
The most active plant extracts, with an IC50 as low as 1.6mug/mL, were obtained from Aspidosperma rigidum (Apocynaceae), Bertholletia excels …
Antimalarial activity of cedronin.
Moretti C, Deharo E, Sauvain M, Jardel C, David PT, Gasquet M. Moretti C, et al. J Ethnopharmacol. 1994 Jun;43(1):57-61. doi: 10.1016/0378-8741(94)90117-1. J Ethnopharmacol. 1994. PMID: 7967650
Cedronin was isolated from Simaba cedron Planchon (Simaroubaceae), a species popularly believed in South America to have antimalarial properties. ...
Cedronin was isolated from Simaba cedron Planchon (Simaroubaceae), a species popularly believed in South America to hav …